Hepatitis E during Tocilizumab Therapy in a Patient with Rheumatoid Arthritis: Case Report and Literature Review
Joint Authors
Sakairi, Toru
Nojima, Yoshihisa
Hiromura, Keiju
Mimura, Toshihide
Koinuma, Kana
Kaneko, Yoriaki
Yamazaki, Yuichi
Okamoto, Hiroaki
Mochida, Satoshi
Nakasatomi, Masao
Maeshima, Akito
Ikeuchi, Hidekazu
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Hepatitis E is an acute self-limiting disease caused by hepatitis E virus (HEV).
Recent reports show that HEV can induce chronic hepatitis or be reactivated in immunocompromised hosts.
We report a 63-year-old woman with rheumatoid arthritis (RA) who developed hepatitis E during treatment with tocilizumab.
Analysis of serially stocked serum samples confirmed that hepatitis was caused by primary infection with HEV and not by viral reactivation.
Her liver function improved after discontinuing tocilizumab and remained within the normal range without reactivation of HEV for >5 years after restarting tocilizumab.
We also reviewed the published cases of hepatitis E that developed during RA treatment.
American Psychological Association (APA)
Ikeuchi, Hidekazu& Koinuma, Kana& Nakasatomi, Masao& Sakairi, Toru& Kaneko, Yoriaki& Maeshima, Akito…[et al.]. 2018. Hepatitis E during Tocilizumab Therapy in a Patient with Rheumatoid Arthritis: Case Report and Literature Review. Case Reports in Rheumatology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1149874
Modern Language Association (MLA)
Ikeuchi, Hidekazu…[et al.]. Hepatitis E during Tocilizumab Therapy in a Patient with Rheumatoid Arthritis: Case Report and Literature Review. Case Reports in Rheumatology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1149874
American Medical Association (AMA)
Ikeuchi, Hidekazu& Koinuma, Kana& Nakasatomi, Masao& Sakairi, Toru& Kaneko, Yoriaki& Maeshima, Akito…[et al.]. Hepatitis E during Tocilizumab Therapy in a Patient with Rheumatoid Arthritis: Case Report and Literature Review. Case Reports in Rheumatology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1149874
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149874
