Antifungal Activity of Crude Extract from the Rhizome and Root of Smilacina japonica A. Gray
Joint Authors
Liu, Wei
Sun, Baozheng
Yang, Manman
Zhang, Ziyue
Zhang, Xiuxiu
Pang, Tingsong
Wang, Shengzheng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
This study aimed to investigate the antifungal activity of hydroalcoholic extract from Smilacina japonica A.
Gray (SJA) against different fungi.
The minimum inhibitory concentration (MIC) for SJA was determined by the broth microdilution method.
The antifungal effects of SJA against Candida albicans were further confirmed by cell growth test and time-kill curve test.
The effects of SJA on the fungal morphology and ultrastructure were also evaluated.
SJA has a broad-spectrum antifungal activity.
The MICs of SJA against different fungi, including fluconazole-sensitive and -resistant Candida albicans, other Candida species, and Cryptococcus neoformans, ranged from 208 μg/ml to 1665 μg/ml.
Furthermore, SJA displayed fungicidal activity against varied fungi and obviously inhibited the hyphal growth of fungi.
The mechanism study revealed that the antifungal activity of SJA might be associated with its effect on the cell morphology and ultrastructure.
American Psychological Association (APA)
Liu, Wei& Sun, Baozheng& Yang, Manman& Zhang, Ziyue& Zhang, Xiuxiu& Pang, Tingsong…[et al.]. 2019. Antifungal Activity of Crude Extract from the Rhizome and Root of Smilacina japonica A. Gray. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1150102
Modern Language Association (MLA)
Liu, Wei…[et al.]. Antifungal Activity of Crude Extract from the Rhizome and Root of Smilacina japonica A. Gray. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1150102
American Medical Association (AMA)
Liu, Wei& Sun, Baozheng& Yang, Manman& Zhang, Ziyue& Zhang, Xiuxiu& Pang, Tingsong…[et al.]. Antifungal Activity of Crude Extract from the Rhizome and Root of Smilacina japonica A. Gray. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1150102
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150102
