Colonic Adenocarcinoma at Advanced Stage in Adolescence: Report of 2 Cases
Joint Authors
Vundamati, Divya S.
Chen, Xiuxu
Singh, Vivekanand
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-28
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Background.
Carcinoma of colon is rare in children and adolescents.
The staging criteria of the carcinoma is the same as those for adults.
However, the pathogenetic background in pediatric cases is different from adults and usually involves mismatch repair gene mutations or familial polyposis syndromes.
Case report.
We describe two adolescents diagnosed with advanced stage colon carcinoma and discuss the histological appearance, testing for mismatch repair genes and contrast- it with carcinoma occurring in the setting of familial polyposis syndrome.
Conclusion.
Colonic carcinoma occurring in pediatric patients should prompt a work-up for mismatch repair gene mutation status.
Despite higher stage of presentation, some of the pediatric patients may respond favorably to chemotherapy and surgical resection.
American Psychological Association (APA)
Vundamati, Divya S.& Chen, Xiuxu& Singh, Vivekanand. 2020. Colonic Adenocarcinoma at Advanced Stage in Adolescence: Report of 2 Cases. Case Reports in Pathology،Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1150384
Modern Language Association (MLA)
Vundamati, Divya S.…[et al.]. Colonic Adenocarcinoma at Advanced Stage in Adolescence: Report of 2 Cases. Case Reports in Pathology No. 2020 (2020), pp.1-3.
https://search.emarefa.net/detail/BIM-1150384
American Medical Association (AMA)
Vundamati, Divya S.& Chen, Xiuxu& Singh, Vivekanand. Colonic Adenocarcinoma at Advanced Stage in Adolescence: Report of 2 Cases. Case Reports in Pathology. 2020. Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1150384
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150384