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Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization
Joint Authors
Lin, Yi-Wen
Lai, Hsiang-Chun
Hsieh, Ching-Liang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-07
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Pain can trigger central amplification called central sensitization, which ultimately results in hyperalgesia and/or allodynia.
Many reports have showed acupuncture has an analgesic effect.
We searched the related article on PubMed database and Cochrane database to discover central sensitization pathway in acupuncture analgesia.
We summarized that acupuncture enhances the descending inhibitory effect and modulates the feeling of pain, thus modifying central sensitization.
The possible mechanisms underlying the analgesic effects of acupuncture include segmental inhibition and the activation of the endogenous opioid, adrenergic, 5-hydroxytryptamine, and N-methyl-D-aspartic acid, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate pathways.
Moreover, acupuncture can locally reduce the levels of inflammatory mediators.
In clinical settings, acupuncture can be used to treat headache, neuropathic pain, low back pain, osteoarthritis, and irritable bowel syndrome.
These mechanisms of acupuncture analgesia may be involved in the alleviation of central sensitization.
American Psychological Association (APA)
Lai, Hsiang-Chun& Lin, Yi-Wen& Hsieh, Ching-Liang. 2019. Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1150386
Modern Language Association (MLA)
Lai, Hsiang-Chun…[et al.]. Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1150386
American Medical Association (AMA)
Lai, Hsiang-Chun& Lin, Yi-Wen& Hsieh, Ching-Liang. Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1150386
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150386