Effect of Moxibustion on Intestinal Microbiome in Acute Gastric Ulcer Rats
Joint Authors
Zhang, Yuan
He, Qi-da
Huang, Miao-sen
Qian, Lin-chao
Zhang, Long-bin
Shen, Jia-cheng
Lian, Lin-yu
Chen, Bao-hua
Liu, Cai-chun
Liu, Mi
Yang, Zhongbao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
In Traditional Chinese Medicine (TCM), moxibustion had been used for thousands of years.
Many clinical case reports and scientific studies had proved that moxibustion had a good effect in treating acute gastric ulcer (AGU).
Some studies had shown that the relative content and species of bacteria in the intestinal would be changed when gastric mucosal injury happened.
However, there was little research on the effect of intestinal microbiome with AGU rats that were treating by moxibustion.
This study is aimed at analyzing the effect of fecal microbiome in rats with AGU by the 16S rDNA sequencing technology.
Male SD rats were established by orally feeding once with 70% ethanol at 4 ml/kg except the control group, then treated by moxibustion in the stomach meridian group (“Liangmen,” “Zusanli”) and the gallbladder meridian group (“Riyue,” “Yanglingquan”) for 5 days.
The 16S rDNA sequencing technology analysis of feces combined with histopathological methods and molecular biological detection methods was used to evaluate the therapeutic mechanism of moxibustion on AGU.
AGU brought cause changes in the number and species of intestinal bacteria.
Moxibustion on stomach meridian group could reduce the area of gastric mucosal injury and regulate the relative content of GAS and EGF.
Moreover, moxibustion on the stomach meridian group could increase the relative content and species of beneficial bacteria in the intestine of rats with AGU.
The relative abundance of intestinal probiotics was significantly upregulated in Alphaproteobacteria, Actinomycetales, and Bacillales.
In addition, moxibustion might promote the repair of gastric mucosal injury by increasing the number and species of beneficial bacteria in the intestine.
American Psychological Association (APA)
He, Qi-da& Huang, Miao-sen& Zhang, Long-bin& Shen, Jia-cheng& Lian, Lin-yu& Zhang, Yuan…[et al.]. 2019. Effect of Moxibustion on Intestinal Microbiome in Acute Gastric Ulcer Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1150396
Modern Language Association (MLA)
He, Qi-da…[et al.]. Effect of Moxibustion on Intestinal Microbiome in Acute Gastric Ulcer Rats. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1150396
American Medical Association (AMA)
He, Qi-da& Huang, Miao-sen& Zhang, Long-bin& Shen, Jia-cheng& Lian, Lin-yu& Zhang, Yuan…[et al.]. Effect of Moxibustion on Intestinal Microbiome in Acute Gastric Ulcer Rats. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1150396
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150396