Intravenous γ Globulin for Intractable Abdominal Pain due to IgA Vasculitis
Joint Authors
Naifa, George
Totikidis, George
Alexiadou, Sonia
Kolona, Christina
Mantadakis, Elpis
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
IgA vasculitis (formerly known as Henoch–Schönlein purpura or anaphylactoid purpura) is a usually benign vasculitis that affects children of school age.
The disease is characterized by the tetrad of palpable purpura, arthralgia/arthritis, abdominal pain, and hematuria.
Treatment of IgA vasculitis is mainly supportive, with administration of simple analgesics.
Corticosteroids have been shown to reduce and/or ameliorate the occurrence of abdominal pain which may be severe.
We present two children with IgA vasculitis and severe abdominal pain despite corticosteroid administration, who responded promptly to intravenous γ globulin (IVIg) with complete resolution of their symptoms and review of the relevant medical literature.
Given the toxicity and/or need for long-term administration of other second-line immunosuppressive therapies in corticosteroid-resistant IgA vasculitis, such as rituximab, cyclosporine, cyclophosphamide, azathioprine, or colchicine, we propose that IVIg may be a useful and safe treatment option, although randomized controlled clinical trials are needed in order to clarify its role in the treatment of abdominal pain in IgA vasculitis.
American Psychological Association (APA)
Naifa, George& Totikidis, George& Alexiadou, Sonia& Kolona, Christina& Mantadakis, Elpis. 2020. Intravenous γ Globulin for Intractable Abdominal Pain due to IgA Vasculitis. Case Reports in Pediatrics،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1150781
Modern Language Association (MLA)
Naifa, George…[et al.]. Intravenous γ Globulin for Intractable Abdominal Pain due to IgA Vasculitis. Case Reports in Pediatrics No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1150781
American Medical Association (AMA)
Naifa, George& Totikidis, George& Alexiadou, Sonia& Kolona, Christina& Mantadakis, Elpis. Intravenous γ Globulin for Intractable Abdominal Pain due to IgA Vasculitis. Case Reports in Pediatrics. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1150781
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150781