Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with 2019 Novel Coronavirus (SARS-CoV-2) Infection
Joint Authors
Kaushik, Ashlesha
Kest, Helen
Colletti, Mario
Goldberg, David
DeBruin, William
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-18
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We report three critically ill pediatric patients (aged 6–10 years), presenting with features of multisystem inflammatory syndrome in children (MIS-C) from April 4 to May 10, 2020, to a tertiary-care center in New Jersey, United States.
All patients tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and were previously healthy.
Clinical presentations were similar with fever, abdominal pain, gastrointestinal complaints, and/or rash.
One patient had altered mental status with cerebrospinal fluid (CSF) findings consistent with aseptic meningitis.
Laboratory values were remarkable for high levels of C-reactive protein, D-dimers, B-type natriuretic peptide (BNP), and troponin in all patients.
All had low albumin levels.
Evaluation for other infectious etiologies was negative.
All of the patients were critically ill, requiring admission to the intensive care unit.
All had circulatory shock and needed inotropes.
Two patients had respiratory failure requiring advanced respiratory support and one had cardiac dysfunction.
All patients received steroids, and two received intravenous immunoglobulin (IVIG).
One patient received tocilizumab.
None of the children died.
MIS-C is a recently recognized pediatric illness spectrum in association with SARS-CoV-2 infection, and clinical characterization is essential for understanding disease mechanisms to inform clinical practice.
American Psychological Association (APA)
Kest, Helen& Kaushik, Ashlesha& DeBruin, William& Colletti, Mario& Goldberg, David. 2020. Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with 2019 Novel Coronavirus (SARS-CoV-2) Infection. Case Reports in Pediatrics،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1150802
Modern Language Association (MLA)
Kest, Helen…[et al.]. Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with 2019 Novel Coronavirus (SARS-CoV-2) Infection. Case Reports in Pediatrics No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1150802
American Medical Association (AMA)
Kest, Helen& Kaushik, Ashlesha& DeBruin, William& Colletti, Mario& Goldberg, David. Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with 2019 Novel Coronavirus (SARS-CoV-2) Infection. Case Reports in Pediatrics. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1150802
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150802