Traditional Chinese Medicine Yimucao Injection Combined with Western Medicine for Preventing Postpartum Hemorrhage after Cesarean Section: A Systematic Review and Meta-Analysis

Joint Authors

Chen, Shichun
Xie, Baocheng
Tian, Hao
Ding, Shaobo
Lu, Chengyu

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-13, 13 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-04-09

Country of Publication

Egypt

No. of Pages

13

Main Subjects

Medicine

Abstract EN

Objective.

Yimucao injection combined with several contraction uterus drugs is in use for preventing postpartum hemorrhage after cesarean section.

The present study is a meta-analysis comparing the efficacy and safety of these drugs.

Methods.

PubMed, Cochrane Library, Embase, the China National Knowledge Infrastructure (CNKI), the Chinese Biomedical Database (CBM), VIP, and Wanfang database were searched until June 2018.

We selected RCTs of Yimucao injection combined with western medicine for preventing postpartum hemorrhage and study quality was assessed using the revised Cochrane risk of bias tool.

Forty-eight RCTs are comprised of 7,330 participants.

Results.

The overall response rate of Yimucao injection combined with western medicine as a class (OR=4.19, 95%CI=2.83, 6.20, P<0.00001) was found to be significantly improved than western medicine alone.

Yimucao injection combined with western medicine group could significantly reduce blood loss in intraoperative (SMD= -1.15, 95%CI= -1.43, -0.87, P<0.00001), compared with control group.

The treatment group could significantly reduce postpartum blood loss within 2 hours (SMD= -1.73, 95%CI= -2.01, -1.46, P<0.00001) and had a significantly lower blood loss within 24 hours (SMD= -1.92, 95%CI= -2.21, -1.63, P<0.00001) than control group.

Additionally, in terms of the safety, Yimucao injection group reduced the risk of adverse events in the course of prevention than the western medicine group.

Conclusions.

This study demonstrated that Yimucao injection combined with western medicine may be more effective for preventing postpartum hemorrhage after cesarean section.

However, high-quality and large multicenter randomized clinical trials will be needed to prove the consequence in the further.

American Psychological Association (APA)

Chen, Shichun& Xie, Baocheng& Tian, Hao& Ding, Shaobo& Lu, Chengyu. 2019. Traditional Chinese Medicine Yimucao Injection Combined with Western Medicine for Preventing Postpartum Hemorrhage after Cesarean Section: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1150877

Modern Language Association (MLA)

Chen, Shichun…[et al.]. Traditional Chinese Medicine Yimucao Injection Combined with Western Medicine for Preventing Postpartum Hemorrhage after Cesarean Section: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1150877

American Medical Association (AMA)

Chen, Shichun& Xie, Baocheng& Tian, Hao& Ding, Shaobo& Lu, Chengyu. Traditional Chinese Medicine Yimucao Injection Combined with Western Medicine for Preventing Postpartum Hemorrhage after Cesarean Section: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1150877

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1150877