The Relationship between Body Mass Index and the Severity of Coronary Artery Disease in Patients Referred for Coronary Angiography
Joint Authors
Gregory, Anne B.
Lester, Kendra K.
Gregory, Deborah M.
Twells, Laurie K.
Midodzi, William K.
Pearce, Neil J.
Source
Cardiology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background and Aim.
Obesity is associated with an increased risk of cardiovascular disease and may be associated with more severe coronary artery disease (CAD); however, the relationship between body mass index [BMI (kg/m2)] and CAD severity is uncertain and debatable.
The aim of this study was to examine the relationship between BMI and angiographic severity of CAD.
Methods.
Duke Jeopardy Score (DJS), a prognostic tool predictive of 1-year mortality in CAD, was assigned to angiographic data of patients ≥18 years of age (N=8,079).
Patients were grouped into 3 BMI categories: normal (18.5–24.9 kg/m2), overweight (25.0–29.9 kg/m2), and obese (≥30 kg/m2); and multivariable adjusted hazard ratios for 1-year all-cause and cardiac-specific mortality were calculated.
Results.
Cardiac risk factor prevalence (e.g., diabetes, hypertension, and hyperlipidemia) significantly increased with increasing BMI.
Unadjusted all-cause and cardiac-specific 1-year mortality tended to rise with incremental increases in DJS, with the exception of DJS 6 (p<0.001).
After adjusting for potential confounders, no significant association of BMI and all-cause (HR 0.70, 95% CI .48–1.02) or cardiac-specific (HR 1.11, 95% CI .64–1.92) mortality was found.
Conclusions.
This study failed to detect an association of BMI with 1-year all-cause or cardiac-specific mortality after adjustment for potential confounding variables.
American Psychological Association (APA)
Gregory, Anne B.& Lester, Kendra K.& Gregory, Deborah M.& Twells, Laurie K.& Midodzi, William K.& Pearce, Neil J.. 2017. The Relationship between Body Mass Index and the Severity of Coronary Artery Disease in Patients Referred for Coronary Angiography. Cardiology Research and Practice،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1150970
Modern Language Association (MLA)
Gregory, Anne B.…[et al.]. The Relationship between Body Mass Index and the Severity of Coronary Artery Disease in Patients Referred for Coronary Angiography. Cardiology Research and Practice No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1150970
American Medical Association (AMA)
Gregory, Anne B.& Lester, Kendra K.& Gregory, Deborah M.& Twells, Laurie K.& Midodzi, William K.& Pearce, Neil J.. The Relationship between Body Mass Index and the Severity of Coronary Artery Disease in Patients Referred for Coronary Angiography. Cardiology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1150970
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150970