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Recurrent Stroke after Transcatheter PFO Closure in Cryptogenic Stroke or Tia: Long-Term Follow-Up
Joint Authors
Mariucci, Elisabetta
Donti, Andrea
Salomone, Luisa
Marcia, Marta
Guidarini, Marta
Formigari, Roberto
Prandstraller, Daniela
Balducci, Anna
Bronzetti, Gabriele
Bonvicini, Marco
Source
Cardiology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
There are few data on the mechanism of recurrent neurological events after transcatheter closure of patent foramen ovale (PFO) in cryptogenic stroke or TIA.
Methods.
We retrospectively reviewed PFO closure procedures for the secondary prevention of cryptogenic stroke/TIA performed between 1999 and 2014 in Bologna, Italy.
Results.
Written questionnaires were completed by 402 patients.
Mean follow-up was 7 ± 3 years.
Stroke recurred in 3.2% (0.5/100 patients-year) and TIA in 2.7% (0.4/100 patients-year).
Ninety-two percent of recurrent strokes were not cryptogenic.
Recurrent stroke was noncardioembolic in 69% of patients, AF related in 15% of patients, device related in 1 patient, and cryptogenic in 1 patient.
AF was diagnosed after the procedure in 21 patients (5.2%).
Multivariate Cox’s proportion hazard model identified age ≥ 55 years at the time of closure (OR 3.16, p=0.007) and RoPE score < 7 (OR 3.21, p=0.03) as predictors of recurrent neurological events.
Conclusion.
Recurrent neurological events after PFO closure are rare, usually noncryptogenic and associated with conventional vascular risk factors or AF related.
Patients older than 55 years of age and those with a RoPE score < 7 are likely to get less benefit from PFO closure.
After transcatheter PFO closure, lifelong strict vascular risk factor control is warranted.
American Psychological Association (APA)
Mariucci, Elisabetta& Donti, Andrea& Salomone, Luisa& Marcia, Marta& Guidarini, Marta& Formigari, Roberto…[et al.]. 2017. Recurrent Stroke after Transcatheter PFO Closure in Cryptogenic Stroke or Tia: Long-Term Follow-Up. Cardiology Research and Practice،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1150991
Modern Language Association (MLA)
Mariucci, Elisabetta…[et al.]. Recurrent Stroke after Transcatheter PFO Closure in Cryptogenic Stroke or Tia: Long-Term Follow-Up. Cardiology Research and Practice No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1150991
American Medical Association (AMA)
Mariucci, Elisabetta& Donti, Andrea& Salomone, Luisa& Marcia, Marta& Guidarini, Marta& Formigari, Roberto…[et al.]. Recurrent Stroke after Transcatheter PFO Closure in Cryptogenic Stroke or Tia: Long-Term Follow-Up. Cardiology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1150991
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1150991