Successful Treatment for Hypercalcemia due to Cosecretion of Parathyroid Hormone-Related Protein and 1,25-Dihydroxyvitamin D3 in Non-Small-Cell Lung Cancer: A Case Report and Literature Review

Joint Authors

Fukunaga, Koichi
Ogawa, Takunori
Miyata, Jun
Kawana, Akihiko
Inoue, Takashi

Source

Case Reports in Pulmonology

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-01-03

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Diseases

Abstract EN

Hypercalcemia of malignancy frequently manifests as paraneoplastic syndrome in patients with solid tumors.

A 71-year-old man was diagnosed with stage IIIB lung squamous cell carcinoma.

Laboratory examination revealed high serum calcium concentration with elevated serum parathyroid hormone-related protein (PTHrP) and 1,25-dihydroxyvitamin D3 levels.

As the patient did not respond to the initial treatment with calcitonin, extracellular fluid infusion, and chemotherapy, systemic prednisolone was administered additionally.

Thus, the levels of serum calcium normalized and PTHrP and 1,25-dihydroxyvitamin D3 decreased simultaneously.

To our knowledge, this is the first case report on the successful treatment of hypercalcemia of malignancy caused by PTHrP and 1,25-dihydroxyvitamin D3 cosecretion in a patient with lung cancer.

American Psychological Association (APA)

Ogawa, Takunori& Miyata, Jun& Fukunaga, Koichi& Kawana, Akihiko& Inoue, Takashi. 2020. Successful Treatment for Hypercalcemia due to Cosecretion of Parathyroid Hormone-Related Protein and 1,25-Dihydroxyvitamin D3 in Non-Small-Cell Lung Cancer: A Case Report and Literature Review. Case Reports in Pulmonology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1151002

Modern Language Association (MLA)

Ogawa, Takunori…[et al.]. Successful Treatment for Hypercalcemia due to Cosecretion of Parathyroid Hormone-Related Protein and 1,25-Dihydroxyvitamin D3 in Non-Small-Cell Lung Cancer: A Case Report and Literature Review. Case Reports in Pulmonology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1151002

American Medical Association (AMA)

Ogawa, Takunori& Miyata, Jun& Fukunaga, Koichi& Kawana, Akihiko& Inoue, Takashi. Successful Treatment for Hypercalcemia due to Cosecretion of Parathyroid Hormone-Related Protein and 1,25-Dihydroxyvitamin D3 in Non-Small-Cell Lung Cancer: A Case Report and Literature Review. Case Reports in Pulmonology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1151002

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1151002