Efficacy of Omalizumab Therapy in an Asthmatic with Low IgE
Joint Authors
R, Divya
Venkitakrishnan, Rajesh
Augustine, Jolsana
Cleetus, Melcy
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Asthma is one of the most common respiratory diseases encountered in clinical practice.
Although the vast majority of asthmatics can be adequately controlled with inhaled steroids and other preventer medications, a small proportion remain uncontrolled.
Anti-IgE treatment with omalizumab has been proposed in patients as a preferred approach in step 5 asthma therapy according to GINA guidelines.
Although therapy with this molecule is approved for patients with atopic asthma and pretreatment serum IgE levels of 30-1500 only, there have been a few reports of its efficacy in subjects outside this reference IgE range.
We report the case of a middle-aged lady with severe corticosteroid-dependent asthma and low serum IgE levels who was successfully treated with 9 months of omalizumab therapy.
She gained good asthma control and was tapered off steroid use by the fifth month of therapy with omalizumab.
The case report stresses the need for further investigation into expanding the spectrum of omalizumab usage in asthma beyond the current IgE suitability range.
American Psychological Association (APA)
R, Divya& Venkitakrishnan, Rajesh& Augustine, Jolsana& Cleetus, Melcy. 2020. Efficacy of Omalizumab Therapy in an Asthmatic with Low IgE. Case Reports in Pulmonology،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1151043
Modern Language Association (MLA)
R, Divya…[et al.]. Efficacy of Omalizumab Therapy in an Asthmatic with Low IgE. Case Reports in Pulmonology No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1151043
American Medical Association (AMA)
R, Divya& Venkitakrishnan, Rajesh& Augustine, Jolsana& Cleetus, Melcy. Efficacy of Omalizumab Therapy in an Asthmatic with Low IgE. Case Reports in Pulmonology. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1151043
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151043