Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers?
Joint Authors
Savino, Elena
Vigna, Luisella
Morelli, Federica
Agnelli, Gianna M.
Napolitano, Filomena
Ratto, Daniela
Occhinegro, Alessandra
Di Iorio, Carmine
Girometta, Carolina
Brandalise, Federico
Rossi, Paola
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-18
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Epidemiological data indicate that subjects affected by obesity have an increased risk of developing mood disorders.
The relationship between obesity and mood disorders is bidirectional.
We assessed whether a Hericium erinaceus treatment improved depression, anxiety, sleep, and binge eating disorders after 8 weeks of supplementation in subjects affected by overweight or obesity under a low calorie diet regimen.
Looking for a possible clinical biomarker, we assessed the serum balance between brain-derived neurotrophic factor (BDNF) and its precursor pro-BDNF before and after H.
erinaceus supplementation.
Seventy-seven volunteers affected by overweight or obesity were recruited at the offices of the Department of Preventive Medicine, Luigi Devoto Clinic of Work, Obesity Centre, at the IRCCS Foundation Policlinico Hospital of Milan (Italy).
Patients were recruited only if they had a mood and/or sleep disorder and/or were binge eating as evaluated through self-assessment questionnaires.
We used two different enzyme-linked immunosorbent assays kits to discriminate circulating levels of pro-BDNF and BDNF.
Eight weeks of oral H.
erinaceus supplementation decreased depression, anxiety, and sleep disorders.
H.
erinaceus supplementation improved mood disorders of a depressive-anxious nature and the quality of the nocturnal rest.
H.
erinaceus increased circulating pro-BDNF levels without any significant change in BDNF circulating levels.
American Psychological Association (APA)
Vigna, Luisella& Morelli, Federica& Agnelli, Gianna M.& Napolitano, Filomena& Ratto, Daniela& Occhinegro, Alessandra…[et al.]. 2019. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers?. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1151057
Modern Language Association (MLA)
Vigna, Luisella…[et al.]. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers?. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1151057
American Medical Association (AMA)
Vigna, Luisella& Morelli, Federica& Agnelli, Gianna M.& Napolitano, Filomena& Ratto, Daniela& Occhinegro, Alessandra…[et al.]. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers?. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1151057
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151057