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The Wound Healing Potential of Aspilia africana (Pers.) C. D. Adams (Asteraceae)
Joint Authors
Kang, Youngmin
Komakech, Richard
Matsabisa, Motlalepula Gilbert
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-21
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Wounds remain one of the major causes of death worldwide.
Over the years medicinal plants and natural compounds have played an integral role in wound treatment.
Aspilia africana (Pers.) C.
D.
Adams which is classified among substances with low toxicity has been used for generations in African traditional medicine to treat wounds, including stopping bleeding even from severed arteries.
This review examined the potential of the extracts and phytochemicals from A.
africana, a common herbaceous flowering plant which is native to Africa in wound healing.
In vitro and in vivo studies have provided strong pharmacological evidences for wound healing effects of A.
africana-derived extracts and phytochemicals.
Singly or in synergy, the different bioactive phytochemicals including alkaloids, saponins, tannins, flavonoids, phenols, terpenoids, β-caryophyllene, germacrene D, α-pinene, carene, phytol, and linolenic acid in A.
africana have been observed to exhibit a very strong anti-inflammatory, antimicrobial, and antioxidant activities which are important processes in wound healing.
Indeed, A.
africana wound healing ability is furthermore due to the fact that it can effectively reduce wound bleeding, hasten wound contraction, increase the concentration of basic fibroblast growth factor (BFGF) and platelet derived growth factor, and stimulate the haematological parameters, including white and red blood cells, all of which are vital components for the wound healing process.
Therefore, these facts may justify why A.
africana is used to treat wounds in ethnomedicine.
American Psychological Association (APA)
Komakech, Richard& Matsabisa, Motlalepula Gilbert& Kang, Youngmin. 2019. The Wound Healing Potential of Aspilia africana (Pers.) C. D. Adams (Asteraceae). Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1151079
Modern Language Association (MLA)
Komakech, Richard…[et al.]. The Wound Healing Potential of Aspilia africana (Pers.) C. D. Adams (Asteraceae). Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1151079
American Medical Association (AMA)
Komakech, Richard& Matsabisa, Motlalepula Gilbert& Kang, Youngmin. The Wound Healing Potential of Aspilia africana (Pers.) C. D. Adams (Asteraceae). Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1151079
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151079