HSCT-GAVE as a Manifestation of Chronic Graft versus Host Disease: A Case Report and Review of the Existing Literature
Joint Authors
Grant, Michael J.
Horwitz, Mitchell E.
Source
Case Reports in Transplantation
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-12
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Gastric antral vascular ectasia or “watermelon stomach” is a significant cause of nonvariceal upper GI bleeding and is characterized by red, tortuous ectatic vessels along longitudinal folds in the gastric antrum.
The existing literature links GAVE to patients with cirrhosis, scleroderma, bone marrow transplantation, and chronic renal failure among other associations, but its pathophysiology remains ill-defined.
Over 30 cases of hematopoietic stem cell transplant-related GAVE (HSCT-GAVE) have been reported in the literature to date and there are likely many more that go undiagnosed or are attributed to another cause of upper gastrointestinal bleeding.
Interestingly, a busulfan-containing conditioning regimen has been the primary factor implicated in the etiology of HSCT-GAVE because this was common to all cases in the literature to date.
Here, we present the first case of HSCT-GAVE in a patient that was treated with a non-busulfan-containing conditioning regimen.
We propose a link between chronic GVHD and the development of HSCT-GAVE that is supported by a similar development of GAVE in patients with systemic sclerosis.
American Psychological Association (APA)
Grant, Michael J.& Horwitz, Mitchell E.. 2018. HSCT-GAVE as a Manifestation of Chronic Graft versus Host Disease: A Case Report and Review of the Existing Literature. Case Reports in Transplantation،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1151202
Modern Language Association (MLA)
Grant, Michael J.& Horwitz, Mitchell E.. HSCT-GAVE as a Manifestation of Chronic Graft versus Host Disease: A Case Report and Review of the Existing Literature. Case Reports in Transplantation No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1151202
American Medical Association (AMA)
Grant, Michael J.& Horwitz, Mitchell E.. HSCT-GAVE as a Manifestation of Chronic Graft versus Host Disease: A Case Report and Review of the Existing Literature. Case Reports in Transplantation. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1151202
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151202