Neutropenic Enterocolitis in a Pediatric Heart Transplant Recipient on Multiple Immunosuppressants
Joint Authors
Miller, Emily E.
Reardon, Leigh Christopher
Source
Case Reports in Transplantation
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Neutropenic enterocolitis (NE) historically primarily affects pediatric patients with leukemia who are undergoing chemotherapy or who have recently received bone marrow transplants.
Although a few case reports have shown NE occurring outside of this typical population, to our knowledge, this is the first published case of NE occurring in the setting of pediatric heart transplant.
This patient was diagnosed several months after pediatric heart transplant, with radiographs showing evidence of pneumatosis intestinalis.
Although NE does not typically affect solid organ transplant patients, this patient had a variety of risk factors that may have predisposed her to development of NE such as severe neutropenia, supratherapeutic tacrolimus level, immunosuppression with cytotoxic agents, and elevated Epstein-Barr viral load.
Fortunately, this patient improved with bowel rest, fluids, antibiotics, and alteration of her immunosuppressive regimen.
However, NE can be fatal, and thus it is an important condition to consider, even in patients without leukemia or on chemotherapeutic regimens.
American Psychological Association (APA)
Miller, Emily E.& Reardon, Leigh Christopher. 2018. Neutropenic Enterocolitis in a Pediatric Heart Transplant Recipient on Multiple Immunosuppressants. Case Reports in Transplantation،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1151213
Modern Language Association (MLA)
Miller, Emily E.& Reardon, Leigh Christopher. Neutropenic Enterocolitis in a Pediatric Heart Transplant Recipient on Multiple Immunosuppressants. Case Reports in Transplantation No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1151213
American Medical Association (AMA)
Miller, Emily E.& Reardon, Leigh Christopher. Neutropenic Enterocolitis in a Pediatric Heart Transplant Recipient on Multiple Immunosuppressants. Case Reports in Transplantation. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1151213
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151213