Elevated Cardiac Troponin T in Patients with Lupus Myositis Presenting with Noncardiac Chest Pain
Joint Authors
Kolasinski, Sharon L.
Katz, Guy
Sundaram, Baskaran
Loizidis, Giorgos
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Patients with systemic lupus erythematosus (SLE) presenting with chest pain pose a unique diagnostic challenge, with causes ranging from cardiopulmonary disease to esophageal disorders and musculoskeletal chest wall pain.
The most common biomarkers for myocardial injury are cardiac troponin T and I (cTnT and cTnI) due to their high sensitivity for the early detection of myocardial infarction.
In the idiopathic inflammatory myopathies, cTnT is commonly elevated, and this reflects skeletal muscle breakdown rather than myocardial damage.
Similar observations have not been reported in SLE myositis to date.
We present two cases of patients with SLE and associated myositis who presented with chest pain and elevated cTnT.
Both patients had a normal cTnI, transthoracic echocardiogram, and cardiac magnetic resonance imaging, likely indicating noncardiac chest pain.
Clinicians should be aware that the specificity of cTnT might be lower in SLE myositis and that cTnI elevation may be more specific in detecting myocardial insult.
American Psychological Association (APA)
Katz, Guy& Kolasinski, Sharon L.& Sundaram, Baskaran& Loizidis, Giorgos. 2020. Elevated Cardiac Troponin T in Patients with Lupus Myositis Presenting with Noncardiac Chest Pain. Case Reports in Rheumatology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1151244
Modern Language Association (MLA)
Katz, Guy…[et al.]. Elevated Cardiac Troponin T in Patients with Lupus Myositis Presenting with Noncardiac Chest Pain. Case Reports in Rheumatology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1151244
American Medical Association (AMA)
Katz, Guy& Kolasinski, Sharon L.& Sundaram, Baskaran& Loizidis, Giorgos. Elevated Cardiac Troponin T in Patients with Lupus Myositis Presenting with Noncardiac Chest Pain. Case Reports in Rheumatology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1151244
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151244