Drug-Induced Liver Injury Associated with the Use of Everolimus in a Liver Transplant Patient
Joint Authors
Valasek, Mark A.
Tsunoda, Shirley
Patel, Serena
Mendler, Michel H.
Source
Case Reports in Transplantation
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Drug-induced liver injury (DILI) has not been previously reported as a complication of treatment with everolimus.
A 56-year-old Caucasian male liver transplant recipient developed DILI after receiving everolimus.
Elevations in transaminase levels occurred within a week of starting everolimus and an upward trend in the transaminase levels continued with supporting histopathologic changes confirmed by liver biopsy.
Within one week of drug discontinuation, his liver enzymes normalized to baseline.
This report includes a brief review of the pharmacokinetic properties of everolimus, a review of the relevant literature, and an analysis using the RUCAM and Naranjo algorithms.
American Psychological Association (APA)
Patel, Serena& Mendler, Michel H.& Valasek, Mark A.& Tsunoda, Shirley. 2018. Drug-Induced Liver Injury Associated with the Use of Everolimus in a Liver Transplant Patient. Case Reports in Transplantation،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1151247
Modern Language Association (MLA)
Patel, Serena…[et al.]. Drug-Induced Liver Injury Associated with the Use of Everolimus in a Liver Transplant Patient. Case Reports in Transplantation No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1151247
American Medical Association (AMA)
Patel, Serena& Mendler, Michel H.& Valasek, Mark A.& Tsunoda, Shirley. Drug-Induced Liver Injury Associated with the Use of Everolimus in a Liver Transplant Patient. Case Reports in Transplantation. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1151247
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151247