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Skin Biophysical Parameters and Patch Test Results in People Predisposing to Xiaotong Tiegao Induced Irritant Contact Dermatitis
Joint Authors
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Xiaotong Tiegao (XTT) is an ancient topical Tibetan medicine plaster which is widely used in China.
Irritant contact dermatitis (ICD) caused by XTT is very common.
It is still unclear why some people are more prone to develop ICD.
The aim of this study is to study the baseline skin biophysical parameters and patch test results in individuals predisposing to XTT induced ICD.
Methods.
During a four-month period, 149 healthy volunteers with ICD and 50 volunteers without ICD after applying XTT were recruited.
The skin biophysical parameters were measured, and contact allergy to 20 common allergens was patch tested, at two weeks after the ICD was recovered.
Results.
There were no significant differences in age and sex between ICD and control groups.
It was found that skin median melanin value (176.50 vs 189.50, P < 0.05, Mann-Whitney U-test) and erythema value (319.90 ± 70.49 vs 347.93 ± 84.55, P < 0.05, Independent-Samples T test) were much lower in ICD than control group.
Overall patch test results were not different, but the positivity rate of nickel sulfate (15.44% vs 4.00%, P < 0.05, Fisher’s exact test) was significantly higher in ICD group.
Conclusions.
In conclusion, people with nickel allergy, lower values of skin melanin, and erythema are predisposing to develop ICD.
American Psychological Association (APA)
Cheng, Hai-Yan& Li, Lin-Feng. 2019. Skin Biophysical Parameters and Patch Test Results in People Predisposing to Xiaotong Tiegao Induced Irritant Contact Dermatitis. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1151365
Modern Language Association (MLA)
Cheng, Hai-Yan& Li, Lin-Feng. Skin Biophysical Parameters and Patch Test Results in People Predisposing to Xiaotong Tiegao Induced Irritant Contact Dermatitis. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1151365
American Medical Association (AMA)
Cheng, Hai-Yan& Li, Lin-Feng. Skin Biophysical Parameters and Patch Test Results in People Predisposing to Xiaotong Tiegao Induced Irritant Contact Dermatitis. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1151365
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151365