Injectable Chemotherapy Downstaged Oral Squamous Cell Carcinoma from Nonresectable to Resectable in a Rescue Dog: Diagnosis, Treatment, and Outcome
Joint Authors
Cai, Shuang
Zhang, Ti
Groer, Chad
Forrest, Melanie
Aires, Daniel
Otte, Vern
Barchman, Sally
Faerber, Abby
Forrest, Marcus Laird
Source
Case Reports in Veterinary Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This case report documents the diagnosis, treatment, and outcome of a nonresectable oral squamous cell carcinoma in a dog with initial poor prognosis.
An approximately 4-year-old female Staffordshire Bull Terrier presented with a large mass on the front of lower jaw which was diagnosed as oral papillary squamous cell carcinoma by histopathology.
CT scans revealed invasion of the cancer to the frenulum of the tongue.
The mass was inoperable due to location, expansiveness, and metastatic lymph nodes.
The dog received 4 treatments of intralesional hyaluronan-platinum conjugates (HylaPlat™, HylaPharm LLC, Lawrence, Kansas) at 3-week intervals.
Clinical chemistry and complete blood count were performed one week after each treatment and results were within normal limits.
Complications included bleeding due to tumor tissue sloughing, as well as a single seizure due to unknown causes.
Upon completion of chemotherapy, CT showed that the mass had regressed and was no longer invading the lingual frenulum, and multiple lymph nodes were free of metastasis.
The mass thus became resectable and the dog successfully underwent rostral bilateral mandibulectomy.
Over one year after chemotherapy and surgery, the cancer remains in complete remission.
American Psychological Association (APA)
Cai, Shuang& Zhang, Ti& Groer, Chad& Forrest, Melanie& Aires, Daniel& Otte, Vern…[et al.]. 2018. Injectable Chemotherapy Downstaged Oral Squamous Cell Carcinoma from Nonresectable to Resectable in a Rescue Dog: Diagnosis, Treatment, and Outcome. Case Reports in Veterinary Medicine،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1151675
Modern Language Association (MLA)
Cai, Shuang…[et al.]. Injectable Chemotherapy Downstaged Oral Squamous Cell Carcinoma from Nonresectable to Resectable in a Rescue Dog: Diagnosis, Treatment, and Outcome. Case Reports in Veterinary Medicine No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1151675
American Medical Association (AMA)
Cai, Shuang& Zhang, Ti& Groer, Chad& Forrest, Melanie& Aires, Daniel& Otte, Vern…[et al.]. Injectable Chemotherapy Downstaged Oral Squamous Cell Carcinoma from Nonresectable to Resectable in a Rescue Dog: Diagnosis, Treatment, and Outcome. Case Reports in Veterinary Medicine. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1151675
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151675