The Liver That Cured Christmas: Case Report of Orthotopic Liver Transplant in a Patient with Hemophilia B
Joint Authors
Harris, Jesse E.
Balk, Jonathan L.
Mobley, Constance M.
Heyne, Kirk
Source
Case Reports in Transplantation
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-18
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Herein, we discuss a case of a 39-year-old male with hemophilia B, who developed end-stage liver disease secondary to nonalcoholic steatohepatitis, that underwent orthotopic liver transplantation (OLT) as a curative means for his liver disease and coagulation disorder.
Existing case reports have demonstrated favorable outcomes in patients outside of the United States who received continuous infusions of recombinant factor IX replacement in the perioperative setting after liver transplant.
Given limitations in the stability of the recombinant factor IX products in the United States, a dosing strategy was comprised of once daily bolus dosing to achieve satisfactory factor IX levels.
Within 48 hours of initial surgery, the patient had sustained factor IX levels above 70% of normal and the patient required no further dosing of factor IX products to date.
This strategy helped facilitate less frequent dosing as well as achieved targeted factor levels while synthetic function of the transplanted liver recovered.
American Psychological Association (APA)
Harris, Jesse E.& Balk, Jonathan L.& Mobley, Constance M.& Heyne, Kirk. 2020. The Liver That Cured Christmas: Case Report of Orthotopic Liver Transplant in a Patient with Hemophilia B. Case Reports in Transplantation،Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1151697
Modern Language Association (MLA)
Harris, Jesse E.…[et al.]. The Liver That Cured Christmas: Case Report of Orthotopic Liver Transplant in a Patient with Hemophilia B. Case Reports in Transplantation No. 2020 (2020), pp.1-3.
https://search.emarefa.net/detail/BIM-1151697
American Medical Association (AMA)
Harris, Jesse E.& Balk, Jonathan L.& Mobley, Constance M.& Heyne, Kirk. The Liver That Cured Christmas: Case Report of Orthotopic Liver Transplant in a Patient with Hemophilia B. Case Reports in Transplantation. 2020. Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1151697
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151697