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Digital Clubbing Is Associated with Higher Serum KL-6 Levels and Lower Pulmonary Function in Patients with Interstitial Lung Disease
Joint Authors
Nishimura, Naoki
Shiraishi, Kazushige
Jinta, Torahiko
Nakaoka, Hiroshi
Tsugitomi, Ryosuke
Okafuji, Kohei
Kitamura, Atsushi
Tomishima, Yutaka
Deshpande, Gautam A.
Tamura, Tomohide
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Although digital clubbing is a common presentation in patients with interstitial lung disease (ILD), little has been reported regarding its role in assessing patients with ILD.
This study evaluated patients with ILD for the presence of clubbing and investigated its association with clinical data.
Methods.
We evaluated patients with ILD who visited the teaching hospital at which the study was conducted, between October 2014 and January 2015.
Clubbing, evaluated using a Vernier caliper for individual patients, was defined as a phalangeal depth ratio > 1.
We examined the association of clubbing with clinical data.
Results.
Of 102 patients with ILD, we identified 17 (16.7%) with clubbing.
The partial pressure of oxygen in arterial blood was lower (65.2 ± 5.9 mmHg versus 80.2 ± 3.1 mmHg; p=0.03), serum Krebs von den Lugen-6 (KL-6) levels were higher (1495.0 ± 277.4 U/mL versus 839.1 ± 70.2 U/mL; p=0.001), and the percent predicted diffusing capacity of carbon monoxide was lower (50.0 ± 6.0 versus 73.5 ± 3.1; p=0.002) in these patients with clubbing.
Conclusions.
Patients with clubbing had lower oxygen levels, higher serum KL-6 levels, and lower pulmonary function than those without clubbing.
American Psychological Association (APA)
Shiraishi, Kazushige& Jinta, Torahiko& Nishimura, Naoki& Nakaoka, Hiroshi& Tsugitomi, Ryosuke& Okafuji, Kohei…[et al.]. 2018. Digital Clubbing Is Associated with Higher Serum KL-6 Levels and Lower Pulmonary Function in Patients with Interstitial Lung Disease. Canadian Respiratory Journal،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1151776
Modern Language Association (MLA)
Shiraishi, Kazushige…[et al.]. Digital Clubbing Is Associated with Higher Serum KL-6 Levels and Lower Pulmonary Function in Patients with Interstitial Lung Disease. Canadian Respiratory Journal No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1151776
American Medical Association (AMA)
Shiraishi, Kazushige& Jinta, Torahiko& Nishimura, Naoki& Nakaoka, Hiroshi& Tsugitomi, Ryosuke& Okafuji, Kohei…[et al.]. Digital Clubbing Is Associated with Higher Serum KL-6 Levels and Lower Pulmonary Function in Patients with Interstitial Lung Disease. Canadian Respiratory Journal. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1151776
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151776