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Leptomeningeal Metastases in a Patient with Castration-Resistant Prostate Cancer
Joint Authors
Hashimoto, Yasuhiro
Koie, Takuya
Hatayama, Yoshiomi
Kimura, Futoshi
Suzuki, Yuichiro
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-14
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A 42-year-old man visited a community hospital with chief complaints of lumbago and dyschesia.
Computed tomography (CT) showed multiple lung, lymph node, and bone metastases and the irregular enlarged prostate with urinary bladder invasion.
Serum prostate-specific antigen (PSA) was 544.0 ng/mL.
Histological evaluation showed adenocarcinoma with the Gleason score 5+4, and the clinical stage was T4N1M1c as an initial diagnosis.
Although androgen deprivation therapy was performed immediately, he had castration-resistant PCa after 3 months.
Therefore, he received 6 courses of docetaxel chemotherapy every 3 weeks.
Serum PSA was decreased to 0.2 ng/mL, and multiple metastases and prostate size were obviously reduced based on CT.
He underwent robot-assisted radical prostatectomy and radiation therapy for prostatic fossa and multiple metastases.
Although serum PSA level remained low, CT showed multiple liver metastases after 3 years from surgery.
He received the combination therapy of cisplatin and etoposide (PE) every 4 weeks.
Liver metastases had complete response.
However, he visited our hospital with complaint of vomiting and a right drooping eyelid after 6 weeks from withdrawal of PE therapy.
T2-weighted magnetic resonance imaging revealed multiple leptomeningeal metastases (LM).
He received RT for the brain and was administered amrubicin.
However, he died of PCa after 6 weeks from the diagnosis of LM.
American Psychological Association (APA)
Koie, Takuya& Hashimoto, Yasuhiro& Suzuki, Yuichiro& Hatayama, Yoshiomi& Kimura, Futoshi. 2020. Leptomeningeal Metastases in a Patient with Castration-Resistant Prostate Cancer. Case Reports in Urology،Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1151795
Modern Language Association (MLA)
Koie, Takuya…[et al.]. Leptomeningeal Metastases in a Patient with Castration-Resistant Prostate Cancer. Case Reports in Urology No. 2020 (2020), pp.1-3.
https://search.emarefa.net/detail/BIM-1151795
American Medical Association (AMA)
Koie, Takuya& Hashimoto, Yasuhiro& Suzuki, Yuichiro& Hatayama, Yoshiomi& Kimura, Futoshi. Leptomeningeal Metastases in a Patient with Castration-Resistant Prostate Cancer. Case Reports in Urology. 2020. Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1151795
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151795