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Gut Microbiota: A New Strategy to Study the Mechanism of Electroacupuncture and Moxibustion in Treating Ulcerative Colitis
Joint Authors
Tang, Yong
Wu, Qiaofeng
Yu, Shu-guang
Wei, Daneng
Xie, Lushuang
Zhuang, Zhiqi
Zhao, Na
Huang, Biao
Zhou, Qizhi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-01
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Previous studies have confirmed that acupuncture and moxibustion is an effective way for treating ulcerative colitis (UC).
However, the exact mechanism is unclear yet.
In this study, DSS-induced UC mice were treated by electroacupuncture and moxibustion, and the genome of intestinal flora was subsequently detected by high-throughput sequencing in order to explore the detailed mechanism in terms of intestinal flora.
The results indicated that the alpha diversity indices and beta diversity of intestinal flora were improved by electroacupuncture and moxibustion treatments, especially by the moxibustion treatment.
These treatments inhibited Streptococcus, Odoribacter, and Allobaculum whereas it facilitated Lactobacillus on genus level.
Further correlation analysis showed that the alpha diversity indices were positively correlated with the percentage of Treg cells in CD4+ cells but negatively correlated with the percentage of Th17 in CD4+ cells.
These data indicated that both electroacupuncture and moxibustion can promote the intestinal flora diversity, providing a new view to understand the relationship between host and microbiome when using some external therapies.
American Psychological Association (APA)
Wei, Daneng& Xie, Lushuang& Zhuang, Zhiqi& Zhao, Na& Huang, Biao& Tang, Yong…[et al.]. 2019. Gut Microbiota: A New Strategy to Study the Mechanism of Electroacupuncture and Moxibustion in Treating Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-16.
https://search.emarefa.net/detail/BIM-1151899
Modern Language Association (MLA)
Wei, Daneng…[et al.]. Gut Microbiota: A New Strategy to Study the Mechanism of Electroacupuncture and Moxibustion in Treating Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-16.
https://search.emarefa.net/detail/BIM-1151899
American Medical Association (AMA)
Wei, Daneng& Xie, Lushuang& Zhuang, Zhiqi& Zhao, Na& Huang, Biao& Tang, Yong…[et al.]. Gut Microbiota: A New Strategy to Study the Mechanism of Electroacupuncture and Moxibustion in Treating Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-16.
https://search.emarefa.net/detail/BIM-1151899
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151899