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Value of the New Spline QTc Formula in Adjusting for Pacing-Induced Changes in Heart Rate
Joint Authors
Nouraei, Hirmand
Bennett, Matthew
Rabkin, Simon W.
Source
Cardiology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aims.
To determine whether a new QTc calculation based on a Spline fit model derived and validated from a large population remained stable in the same individual across a range of heart rates (HRs).
Second, to determine whether this formula incorporating QRS duration can be of value in QT measurement, compared to direct measurement of the JT interval, during ventricular pacing.
Methods.
Individuals (N=30; 14 males) aged 51.9 ± 14.3 years were paced with decremental atrial followed by decremental ventricular pacing.
Results.
The new QTc changed minimally with shorter RR intervals, poorly fit even a linear relationship, and did not fit a second-order polynomial.
In contrast, the Bazett formula (QTcBZT) showed a steep and marked increase in QTc with shorter RR intervals.
For atrial pacing data, QTcBZT was fit best by a second-order polynomial and demonstrated a dramatic increase in QTc with progressively shorter RR intervals.
For ventricular pacing, the new QTc minus QRS duration did not meaningfully change with HR in contrast to the HR dependency of QTcBZT and JT interval.
Conclusion.
The new QT correction formula is minimally impacted by HR acceleration induced by atrial or ventricular pacing.
The Spline QTc minus QRS duration is an excellent method to estimate QTc in ventricular paced complexes.
American Psychological Association (APA)
Nouraei, Hirmand& Bennett, Matthew& Rabkin, Simon W.. 2018. Value of the New Spline QTc Formula in Adjusting for Pacing-Induced Changes in Heart Rate. Cardiology Research and Practice،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1151991
Modern Language Association (MLA)
Nouraei, Hirmand…[et al.]. Value of the New Spline QTc Formula in Adjusting for Pacing-Induced Changes in Heart Rate. Cardiology Research and Practice No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1151991
American Medical Association (AMA)
Nouraei, Hirmand& Bennett, Matthew& Rabkin, Simon W.. Value of the New Spline QTc Formula in Adjusting for Pacing-Induced Changes in Heart Rate. Cardiology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1151991
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1151991