Arterial Stiffness in Breast Cancer Patients Treated with Anthracycline and Trastuzumab-Based Regimens
Joint Authors
Yersal, Özlem
Eryilmaz, Ufuk
Akdam, Hakan
Barutca, Sabri
Meydan, Nezih
Source
Cardiology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aims.
Cardiovascular diseases are the primary cause of premature morbidity and mortality in early breast cancer patients after treatment with cardiotoxic chemotherapeutic agents.
Arterial stiffness is an independent risk factor for future cardiovascular diseases and can be used as a predictive marker of subclinical cardiac damage.
The aim of this study is to analyze the arterial stiffness in breast cancer patients who are in the follow-up period after receiving anthracycline-based chemotherapy regimens with trastuzumab.
Methods and Material.
We enrolled 45 HER2-positive breast cancer patients who are on follow-up at least for six months after completion of adjuvant chemotherapy with trastuzumab, and cardiovascular risk matched 30 control volunteers.
The measurements were done with pulse wave analyzing machine.
Results.
Mean pulse wave velocity was higher in breast cancer patients compared to controls.
The pulse wave velocity was significantly higher in patients receiving aromatase inhibitors compared to patients under tamoxifen.
It was also significantly higher in postmenopausal breast cancer patients than postmenopausal controls.
Conclusions.
Arterial stiffness measurements may predict the breast cancer survivors with higher risk for cardiovascular events earlier in the follow-up period, and necessary preventive approaches and/or treatments can be applied.
American Psychological Association (APA)
Yersal, Özlem& Eryilmaz, Ufuk& Akdam, Hakan& Meydan, Nezih& Barutca, Sabri. 2018. Arterial Stiffness in Breast Cancer Patients Treated with Anthracycline and Trastuzumab-Based Regimens. Cardiology Research and Practice،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1152060
Modern Language Association (MLA)
Yersal, Özlem…[et al.]. Arterial Stiffness in Breast Cancer Patients Treated with Anthracycline and Trastuzumab-Based Regimens. Cardiology Research and Practice No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1152060
American Medical Association (AMA)
Yersal, Özlem& Eryilmaz, Ufuk& Akdam, Hakan& Meydan, Nezih& Barutca, Sabri. Arterial Stiffness in Breast Cancer Patients Treated with Anthracycline and Trastuzumab-Based Regimens. Cardiology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1152060
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152060