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Plasma Chemerin Levels Are Increased in ST Elevation Myocardial Infarction Patients with High Thrombus Burden
Joint Authors
Ateş, Ahmet Hakan
Arslan, Uğur
Yanık, Ahmet
Aksakal, Aytekin
Özdemir, Metin
Kul, Selim
Source
Cardiology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To investigate plasma chemerin levels in ST elevation myocardial infarction (STEMI) patients and find out possible relationships between plasma chemerin levels and angiographic characteristics.
Patients and Methods.
Ninety-seven consecutive patients who presented with STEMI and underwent primary percutaneous coronary intervention (PCI) with coronary stents were enrolled, and 30 age- and sex-matched patients with stable angina pectoris who underwent coronary angiography formed the control group.
Angiographic characteristics of the patients including thrombolysis in myocardial infarction (TIMI) thrombus and Gensini scores were noted.
Blood samples were taken to detect several biochemical markers including plasma chemerin levels at the admission to hospital.
Results.
Serum chemerin and C-reactive protein (CRP) levels were significantly increased in patients with STEMI.
Among STEMI patients, serum chemerin levels were significantly higher in patients with high thrombus burden (581.5 ± 173.7 versus 451.3 ± 101.2 mg/dL, p<0.001).
CRP levels and peak creatine kinase-MB (CK-MB) levels were higher, and left ventricular ejection fraction and post-PCI TIMI flow were lower in patients with high thrombus burden.
After multivariate analysis, serum chemerin levels were also higher in patients with high thrombus grade (odds ratio: 1.009 (1.005–1.014), p<0.001).
Besides, serum chemerin levels were also found to be significantly correlated with CRP r=0.47,p<0.001 and peak CK-MB r=0.376,p<0.001 levels.
Conclusions.
Results from our study have demonstrated for the first time that chemerin levels were higher in STEMI patients with greater thrombus burden and higher level of inflammation.
American Psychological Association (APA)
Ateş, Ahmet Hakan& Arslan, Uğur& Aksakal, Aytekin& Yanık, Ahmet& Özdemir, Metin& Kul, Selim. 2018. Plasma Chemerin Levels Are Increased in ST Elevation Myocardial Infarction Patients with High Thrombus Burden. Cardiology Research and Practice،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1152062
Modern Language Association (MLA)
Ateş, Ahmet Hakan…[et al.]. Plasma Chemerin Levels Are Increased in ST Elevation Myocardial Infarction Patients with High Thrombus Burden. Cardiology Research and Practice No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1152062
American Medical Association (AMA)
Ateş, Ahmet Hakan& Arslan, Uğur& Aksakal, Aytekin& Yanık, Ahmet& Özdemir, Metin& Kul, Selim. Plasma Chemerin Levels Are Increased in ST Elevation Myocardial Infarction Patients with High Thrombus Burden. Cardiology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1152062
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152062