Expression Status of PIWIL1 as a Prognostic Marker of Colorectal Cancer
Joint Authors
Sun, Rui
Gao, Chun-li
Li, Dong-hai
Li, Bo-jun
Ding, Yan-hong
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The PIWI-like protein 1 (PIWIL1) plays a crucial role in stem cell proliferation, embryogenesis, growth, and development, as well as differentiation and maturation in multiple organisms.
The relationships between PIWIL1 expression and clinicopathological features of colorectal cancer (CRC) patients were analyzed by us.
Survival analysis was performed using the Kaplan-Meier method and Cox’s proportional hazards model.
The high expression rate of PIWIL1 in the cancer tissue was obviously higher than that in the corresponding adjacent tissue.
The expression of PIWIL1 was closely related to the tumor differentiation degree, infiltration depth, lymphovascular invasion, lymph node metastasis, and TNM stage.
The Kaplan-Meier survival model suggested that the survival time of CRC patients in the high PIWIL1 expression group was notably lower than that in the low PIWIL1 expression group.
High PIWIL1 expression suggests a poor prognosis for CRC patients, and PIWIL1 can serve as an important molecular marker for predicting the prognosis of CRC patients.
American Psychological Association (APA)
Sun, Rui& Gao, Chun-li& Li, Dong-hai& Li, Bo-jun& Ding, Yan-hong. 2017. Expression Status of PIWIL1 as a Prognostic Marker of Colorectal Cancer. Disease Markers،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1152153
Modern Language Association (MLA)
Sun, Rui…[et al.]. Expression Status of PIWIL1 as a Prognostic Marker of Colorectal Cancer. Disease Markers No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1152153
American Medical Association (AMA)
Sun, Rui& Gao, Chun-li& Li, Dong-hai& Li, Bo-jun& Ding, Yan-hong. Expression Status of PIWIL1 as a Prognostic Marker of Colorectal Cancer. Disease Markers. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1152153
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152153