Usefulness of Positron Emission Tomography in the Examination of Hilar and Mediastinal Lymphadenopathies in Patients with Suspicion of Lung Cancer
Joint Authors
Carreira, J. M.
Valdés Cuadrado, Luis
Ruano-Ravina, Alberto
Pereiro-Brea, Tara
Golpe-Gómez, Antonio
Golpe-Sánchez, Antonio Miguel
Martinez-de-Alegria, Anxo
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Lung cancer is a major health problem.
Mediastinal staging performed with the aid of imaging techniques is essential for appropriate disease treatment and prognosis.
Accordingly, this study aimed to ascertain the usefulness of positron emission tomography (PET) in mediastinal staging, establish the best maximum standardized uptake value (SUVmax) cutoff point, compare its usefulness to that of computed tomography (CT), and determine the influence of histological tumour subtype.
Methods.
We conducted a retrospective study across a period of 3 years on 128 patients with suspicion of lung cancer and analyzed their demographic and radiological characteristics using CT and PET to perform the mediastinal examination.
Histology was regarded as the gold standard.
Results.
PET displayed a high sensitivity (95%) and negative predictive value (NPV) (92%), outperforming CT (89% and 85%, respectively).
Percentage agreement with histology was also higher (0.207 and 0.241 for CT and PET, respectively; p<0.001).
Taking an SUVmax value of 0.5 as that which would ensure greatest diagnostic accuracy, S and NPV were 100%, though percentage agreement did not increase (0.189; p<0.001).
PET discriminatory power was not affected by histological tumour subtype.
Conclusions.
The results of our study indicate that PET might be a useful test for examination of the mediastinum in lung cancer patients.
Its high NPV suggests that the absence of mediastinal uptake could be used to proceed to surgical treatment without the need for further tests or examinations.
Nevertheless, studies directly aimed to answer this specific question are needed.
American Psychological Association (APA)
Pereiro-Brea, Tara& Golpe-Gómez, Antonio& Golpe-Sánchez, Antonio Miguel& Valdés Cuadrado, Luis& Martinez-de-Alegria, Anxo& Carreira, J. M.…[et al.]. 2020. Usefulness of Positron Emission Tomography in the Examination of Hilar and Mediastinal Lymphadenopathies in Patients with Suspicion of Lung Cancer. Canadian Respiratory Journal،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1152202
Modern Language Association (MLA)
Pereiro-Brea, Tara…[et al.]. Usefulness of Positron Emission Tomography in the Examination of Hilar and Mediastinal Lymphadenopathies in Patients with Suspicion of Lung Cancer. Canadian Respiratory Journal No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1152202
American Medical Association (AMA)
Pereiro-Brea, Tara& Golpe-Gómez, Antonio& Golpe-Sánchez, Antonio Miguel& Valdés Cuadrado, Luis& Martinez-de-Alegria, Anxo& Carreira, J. M.…[et al.]. Usefulness of Positron Emission Tomography in the Examination of Hilar and Mediastinal Lymphadenopathies in Patients with Suspicion of Lung Cancer. Canadian Respiratory Journal. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1152202
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152202