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Can Mitochondria DNA Provide a Novel Biomarker for Evaluating the Risk and Prognosis of Colorectal Cancer?
Joint Authors
Shuwen, Han
Xi, Yang
Yuefen, Pan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-16
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Colorectal cancer (CRC) was one of the most frequent cancers worldwide.
Accurate risk and prognosis evaluation could obtain better quality of life and longer survival time for the patients.
Current research hotspot was focus on the gene biomarker to evaluate the risk and prognosis.
Mitochondrion contains its own DNA and regulates self-replicating so that it can be as a candidate biomarker for evaluating the risk and prognosis of colorectal cancer.
But there were already huge controversies on this issue.
The review was to summarize current viewpoints of the controversial issues and described our understanding from the four aspects including mtDNA copy number, mitochondrial displacement loop, mtDNA variation, and mtDNA microsatellite instability, wishing the summary of the mtDNA in colorectal cancer could provide a meaningful reference or a valuable direction in the future studies.
American Psychological Association (APA)
Shuwen, Han& Xi, Yang& Yuefen, Pan. 2017. Can Mitochondria DNA Provide a Novel Biomarker for Evaluating the Risk and Prognosis of Colorectal Cancer?. Disease Markers،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1152364
Modern Language Association (MLA)
Shuwen, Han…[et al.]. Can Mitochondria DNA Provide a Novel Biomarker for Evaluating the Risk and Prognosis of Colorectal Cancer?. Disease Markers No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1152364
American Medical Association (AMA)
Shuwen, Han& Xi, Yang& Yuefen, Pan. Can Mitochondria DNA Provide a Novel Biomarker for Evaluating the Risk and Prognosis of Colorectal Cancer?. Disease Markers. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1152364
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152364