![](/images/graphics-bg.png)
Myocardial Scar on Surface ECG: Selvester Score, but Not Fragmentation, Predicts Response to CRT
Joint Authors
Cavarretta, Elena
Ricciardi, Giuseppe
Sciarra, Luigi
Nesti, Martina
Perini, Alessandro Paoletti
Bani, Rossella
Cartei, Stella
Checchi, Luca
Pieragnoli, Paolo
Michelotti, Federica
Mascioli, Giosuè
Source
Cardiology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-21
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Purpose.
Myocardial scar is directly related to the response to CRT after implantation.
The extent of myocardial scar can be detected not only by cardiac magnetic resonance but also by two electrocardiographic scores: fragmented QRS (fQRS) and Selvester score (SSc).
The aim of our study is to compare the role of baseline SSc and fQRS in predicting response to CRT in a cohort of heart failure patients with true left bundle branch block (LBBB).
As a secondary endpoint, we assessed the association of both scores with overall and cardiac mortality, heart failure hospitalizations, ventricular arrhythmias requiring ICD intervention, and major adverse cardiovascular event (MACE).
Methods.
We evaluated fQRS and SSc of 178 consecutive HF patients with severe systolic dysfunction (LVEF ≤ 35%), NYHA class II-III despite optimal medical treatment, and true-LBBB.
Response to CRT was defined as the improvement of LVEF of at least 10% or as the reduction of LVESV of at least 15% at a 6-month follow-up.
Each endpoint was related to fQRS and SSc.
Results.
SSc ≥7 was significantly associated with the absence of echocardiographic response to CRT (OR: 0.327; 95% C.I.
0.155–0.689; p=0.003), while the presence of fQRS at baseline ECG was not (OR: 1.133; 95% C.I.
0.539–2.381; p=0.742).
No correlation was found between SSc and overall mortality, cardiac death, ventricular arrhythmias, hospitalizations due to heart failure, or for MACE.
Similar results were observed between fQRS and all secondary endpoints.
Conclusion.
In HF patients with true-LBBB and LVEF ≤35% eligible for CRT, myocardial scar assessed by calculating the SSc on preimplant ECG is an independent predictor of nonresponse after multiple adjustments.
Neither SSc nor fQRS is associated with overall and cardiac death, ventricular arrhythmias, or hospitalization for heart failure at a 24-month follow-up.
American Psychological Association (APA)
Nesti, Martina& Perini, Alessandro Paoletti& Bani, Rossella& Cartei, Stella& Checchi, Luca& Ricciardi, Giuseppe…[et al.]. 2020. Myocardial Scar on Surface ECG: Selvester Score, but Not Fragmentation, Predicts Response to CRT. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1152367
Modern Language Association (MLA)
Nesti, Martina…[et al.]. Myocardial Scar on Surface ECG: Selvester Score, but Not Fragmentation, Predicts Response to CRT. Cardiology Research and Practice No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1152367
American Medical Association (AMA)
Nesti, Martina& Perini, Alessandro Paoletti& Bani, Rossella& Cartei, Stella& Checchi, Luca& Ricciardi, Giuseppe…[et al.]. Myocardial Scar on Surface ECG: Selvester Score, but Not Fragmentation, Predicts Response to CRT. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1152367
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152367