The Association of New-Onset Atrial Fibrillation and Risk of Cancer: A Systematic Review and Meta-Analysis
Joint Authors
Ma, Changsheng
Zhang, Mengxia
Li, Lin-ling
Zhao, Qian-qian
Peng, Xiao-dong
Wu, Kui
Li, Xin
Ruan, Yan-Fei
Bai, Rong
Liu, Nian
Source
Cardiology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
There are distinct results for the relationship between new-onset atrial fibrillation (NOAF) and subsequent incident cancer.
To date, no systematic analysis has been conducted on this issue.
This study aims to explore the relationship between NOAF and the risk of developing cancer through a meta-analysis with a large sample size.
Methods.
Electronic databases, such as PubMed and EMBASE, were searched for published relevant studies on NOAF patients diagnosed with cancer after and during follow-ups, including reported records of baseline information and the statistical result of morbidity.
Two investigators independently reviewed the articles and extracted the data using uniform standards and definitions.
The meta-analysis was conducted using the Cochrane Program Review Manager.
Results.
This meta-analysis consisted of five cohort studies and one case-control study, which comprised 533,514 participants.
The pooled relative risk (RR) for incident cancer was 1.24 (95% CI: 1.10–1.39, P=0.0003).
The temporal trend analysis demonstrated that an increased risk of cancer was observed during the initial 90 days (RR: 3.44, 95% CI: 2.29–5.57, P<0.00001), but not after that.
Lung cancer (RR: 1.51, 95% CI: 1.47–1.55, P<0.00001) was associated with NOAF, but not colorectal cancer and breast cancer.
Conclusion.
This meta-analysis provides evidence that NOAF is associated with increased risk of cancer.
The risk of incident cancer particularly increases within 90 days after NOAF diagnosis, but not after that.
American Psychological Association (APA)
Zhang, Mengxia& Li, Lin-ling& Zhao, Qian-qian& Peng, Xiao-dong& Wu, Kui& Li, Xin…[et al.]. 2020. The Association of New-Onset Atrial Fibrillation and Risk of Cancer: A Systematic Review and Meta-Analysis. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1152372
Modern Language Association (MLA)
Zhang, Mengxia…[et al.]. The Association of New-Onset Atrial Fibrillation and Risk of Cancer: A Systematic Review and Meta-Analysis. Cardiology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1152372
American Medical Association (AMA)
Zhang, Mengxia& Li, Lin-ling& Zhao, Qian-qian& Peng, Xiao-dong& Wu, Kui& Li, Xin…[et al.]. The Association of New-Onset Atrial Fibrillation and Risk of Cancer: A Systematic Review and Meta-Analysis. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1152372
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152372