Comparison of the CAMI-NSTEMI and GRACE Risk Model for Predicting In-Hospital Mortality in Chinese Non-ST-Segment Elevation Myocardial Infarction Patients
Joint Authors
Wang, Peng
Cong, Hongliang
Zhang, Ying
Liu, Yujie
Source
Cardiology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
The ability of risk models to predict in-hospital mortality and the influence on downstream therapeutic strategy has not been fully investigated in Chinese Non-ST-segment elevation myocardial infarction (NSTEMI) patients.
Thus, we sought to validate and compare the performance of the Global Registry of Acute Coronary Events risk model (GRM) and China Acute Myocardial Infarction risk model (CRM) and investigate impacts of the two models on the selection of downstream therapeutic strategies among these patients.
Methods.
We identified 2587 consecutive patients with NSTEMI.
The primary endpoint was in-hospital death.
For each patient, the predicted mortality was calculated according to GRM and CRM, respectively.
The area under the receiver operating characteristic curve (AUC), Hosmer–Lemeshow (H–L) test, and net reclassification improvement (NRI) were used to assess the performance of models.
Results.
In-hospital death occurred in 4.89% (126/2587) patients.
Compared to GRM, CRM demonstrated a larger AUC (0.809 versus 0.752, p<0.0001), less discrepancy between observed and predicted mortality (H–L χ2: 22.71 for GRM, p=0.0038 and 10.25 for CRM, p=0.2479), and positive NRI (0.3311, p<0.0001), resulting in a significant change of downstream therapeutic strategy.
Conclusion.
In Chinese NSTEMI patients, the CRM provided a more accurate estimation for in-hospital mortality, and application of the CRM instead of the GRM changes the downstream therapeutic strategy remarkably.
American Psychological Association (APA)
Wang, Peng& Cong, Hongliang& Zhang, Ying& Liu, Yujie. 2020. Comparison of the CAMI-NSTEMI and GRACE Risk Model for Predicting In-Hospital Mortality in Chinese Non-ST-Segment Elevation Myocardial Infarction Patients. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1152374
Modern Language Association (MLA)
Wang, Peng…[et al.]. Comparison of the CAMI-NSTEMI and GRACE Risk Model for Predicting In-Hospital Mortality in Chinese Non-ST-Segment Elevation Myocardial Infarction Patients. Cardiology Research and Practice No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1152374
American Medical Association (AMA)
Wang, Peng& Cong, Hongliang& Zhang, Ying& Liu, Yujie. Comparison of the CAMI-NSTEMI and GRACE Risk Model for Predicting In-Hospital Mortality in Chinese Non-ST-Segment Elevation Myocardial Infarction Patients. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1152374
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152374