Usefulness of Age-Stratified N-Terminal Prohormone of Brain Natriuretic Peptide for Diagnosing Kawasaki Disease
Joint Authors
Cho, Hwa Jin
Song, Eun Song
Cho, Young Kuk
Kang, Gaeun
Lee, Sang Hoon
Yoon, Somy
Hong, Seunghee
Yang, Eun Mi
Eom, Gwang Hyeon
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
N-terminal prohormone of brain natriuretic peptide (NT-proBNP) was recently reported as a biomarker for diagnosing Kawasaki disease (KD).
The basal NT-proBNP level, however, gradually decreases with age.
We investigated the usefulness of an age-stratified cutoff value of NT-proBNP for diagnosing KD.
All the patients enrolled in this study visited Chonnam National University Hospital between December 2007 and March 2016.
The KD groups consisted of 214 patients with complete KD and 129 patients with incomplete KD.
The control group included 62 children with simple febrile illness but without heart disease.
Laboratory data including NT-proBNP level were evaluated.
Each group was divided into subgroups according to patient age (<6 months, 6–12 months, 12–24 months, and >24 months), and different cutoff values of NT-proBNP were calculated.
The cutoff values of NT-proBNP used to diagnose total KD and incomplete KD were 762 and 762 pg/mL (<6 months), 310 and 310 pg/mL (6–12 months), 326 and 326 pg/mL (12–24 months), and 208 and 137 pg/mL (>24 months), respectively.
In conclusion, age-stratified NT-proBNP is a useful biomarker for the differential diagnosis of KD in patients with a simple febrile illness.
American Psychological Association (APA)
Lee, Sang Hoon& Song, Eun Song& Yoon, Somy& Hong, Seunghee& Cho, Hwa Jin& Yang, Eun Mi…[et al.]. 2017. Usefulness of Age-Stratified N-Terminal Prohormone of Brain Natriuretic Peptide for Diagnosing Kawasaki Disease. Disease Markers،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1152423
Modern Language Association (MLA)
Lee, Sang Hoon…[et al.]. Usefulness of Age-Stratified N-Terminal Prohormone of Brain Natriuretic Peptide for Diagnosing Kawasaki Disease. Disease Markers No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1152423
American Medical Association (AMA)
Lee, Sang Hoon& Song, Eun Song& Yoon, Somy& Hong, Seunghee& Cho, Hwa Jin& Yang, Eun Mi…[et al.]. Usefulness of Age-Stratified N-Terminal Prohormone of Brain Natriuretic Peptide for Diagnosing Kawasaki Disease. Disease Markers. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1152423
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152423