The Brain-Heart Connection in Takotsubo Syndrome: The Central Nervous System, Sympathetic Nervous System, and Catecholamine Overload
Joint Authors
Hu, Xin-qun
Wang, Xiaopu
Pei, Junyu
Source
Cardiology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-09
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Takotsubo syndrome (TTS), also known as stress cardiomyopathy, is a type of acute heart failure syndrome triggered by intense psychological or physiological stress.
TTS typically manifests as acute chest pain, dyspnea or syncope that mimics an acute myocardial infarction but does not involve coronary artery obstruction.
The current understanding of the pathogenesis of TTS suggests that sympathetic nervous system (SNS) activation plays a central role.
Specifically, stress can activate the SNS and lead to the over-release of catecholamine, which have toxic effects on myocardial tissue when present at excessive levels.
However, the brain changes associated with TTS and the connection between the brain and the heart in patients with this disease remain unclear.
In recent years, several published reports have revealed the role of this brain-heart connection in the pathogenesis of TTS.
This review summarizes recent studies regarding SNS activation, catecholamine overload, and the brain-heart connection in patients with TTS from both pathophysiological and mechanistic aspects.
American Psychological Association (APA)
Wang, Xiaopu& Pei, Junyu& Hu, Xin-qun. 2020. The Brain-Heart Connection in Takotsubo Syndrome: The Central Nervous System, Sympathetic Nervous System, and Catecholamine Overload. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1152444
Modern Language Association (MLA)
Wang, Xiaopu…[et al.]. The Brain-Heart Connection in Takotsubo Syndrome: The Central Nervous System, Sympathetic Nervous System, and Catecholamine Overload. Cardiology Research and Practice No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1152444
American Medical Association (AMA)
Wang, Xiaopu& Pei, Junyu& Hu, Xin-qun. The Brain-Heart Connection in Takotsubo Syndrome: The Central Nervous System, Sympathetic Nervous System, and Catecholamine Overload. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1152444
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152444