Sex Difference in Risk Factors, GRACE Scores, and Management among Post-Acute Coronary Syndrome Patients in Sri Lanka
Joint Authors
Wijeyaratne, S. M.
Ranasinghe, P.
Galappatty, Priyadarshani
Bataduwaarachchi, Vipula
Galappatthy, Gamini
Senerath, Upul
Ekanayaka, R. A. I.
Source
Cardiology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To assess sex-based differences in the prevalence of risk factor, their management, and differences in the prognosis among acute coronary syndrome (ACS) in Sri Lanka.
Methods.
Patients diagnosed with ACS were recruited from hospitals throughout the island.
The Joint European Societies guidelines were used to assess recommended targets for coronary heart disease risk factors, and the GRACE score was used to assess the post-ACS prognosis.
Age-adjusted regression was performed to calculate odds ratios for men versus women in risk factor control.
Results.
A total of 2116 patients, of whom 1242 (58.7%) were men, were included.
Significant proportion of women were nonsmokers; OR = 0.11 (95% CI 0.09 to 0.13).
The prevalence of hypertension (p<0.001), diabetes (p<0.001), and dyslipidemia (p=0.004) was higher in women.
The LDL-C target was achieved in a significantly higher percentage of women (12.6%); OR = 0.33 (95% CI 0.10 to 1.05).
When stratified by age, no significant differences were observed in achieving the risk factor targets or management strategies used except for fasting blood sugar (p<0.05) where more men achieved control target in both age categories.
Majority of the ACS patients had either high or intermediate risk for one-year mortality as per the GRACE score.
In-hospital and 1-year mean mortality risk was significantly higher among men of less than 65 years of age (p<0.05).
Conclusions.
Smoking is significantly lower among Sri Lankan women diagnosed with ACS.
However, hypertension, diabetes, and dyslipidemia were more prevalent among them.
There was no difference in primary and secondary preventive strategies and management in both sexes but could be further improved in both groups.
American Psychological Association (APA)
Galappatty, Priyadarshani& Bataduwaarachchi, Vipula& Ranasinghe, P.& Galappatthy, Gamini& Senerath, Upul& Wijeyaratne, S. M.…[et al.]. 2020. Sex Difference in Risk Factors, GRACE Scores, and Management among Post-Acute Coronary Syndrome Patients in Sri Lanka. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1152461
Modern Language Association (MLA)
Galappatty, Priyadarshani…[et al.]. Sex Difference in Risk Factors, GRACE Scores, and Management among Post-Acute Coronary Syndrome Patients in Sri Lanka. Cardiology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1152461
American Medical Association (AMA)
Galappatty, Priyadarshani& Bataduwaarachchi, Vipula& Ranasinghe, P.& Galappatthy, Gamini& Senerath, Upul& Wijeyaratne, S. M.…[et al.]. Sex Difference in Risk Factors, GRACE Scores, and Management among Post-Acute Coronary Syndrome Patients in Sri Lanka. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1152461
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152461