Pathophysiological and Genetic Aspects of Vascular Calcification
Joint Authors
Escobar Guzman, Luis Fernando
Escobar Guzman, Cristian Andres
Lopes, Neuza Helena Moreira
Source
Cardiology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Recent evidence suggests that vascular calcification is an independent cardiovascular risk factor (CRF) of morbidity and mortality.
New studies point out the existence of a complex physiopathological mechanism that involves inflammation, oxidation, the release of chemical mediators, and genetic factors that promote the osteochondrogenic differentiation of vascular smooth muscle cells (VSMC).
This review will evaluate the main mechanisms involved in the pathophysiology and genetics modulation of the process of vascular calcification.
Objective.
A systematic review of the pathophysiology factors involved in vascular calcification and its genetic influence was performed.
Methods.
A systematic review was conducted in the Medline and PubMed databases and were searched for studies concerning vascular calcification using the keywords and studies published until 2020/01 in English.
Inclusion Criteria.
Studies in vitro, animal models, and humans.
These include cohort (both retrospective and prospective cohort studies), case-control, cross-sectional, and systematic reviews.
Exclusion Criteria.
Studies before 2003 of the existing literature.
American Psychological Association (APA)
Escobar Guzman, Luis Fernando& Escobar Guzman, Cristian Andres& Lopes, Neuza Helena Moreira. 2020. Pathophysiological and Genetic Aspects of Vascular Calcification. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1152480
Modern Language Association (MLA)
Escobar Guzman, Luis Fernando…[et al.]. Pathophysiological and Genetic Aspects of Vascular Calcification. Cardiology Research and Practice No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1152480
American Medical Association (AMA)
Escobar Guzman, Luis Fernando& Escobar Guzman, Cristian Andres& Lopes, Neuza Helena Moreira. Pathophysiological and Genetic Aspects of Vascular Calcification. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1152480
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152480