Long Noncoding RNAs as Biomarkers in Cancer
Joint Authors
Glavač, Damjan
Bolha, Luka
Ravnik-Glavač, Metka
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-29
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Long noncoding RNAs (lncRNAs) are a relatively well-characterized class of noncoding RNA (ncRNA) molecules, involved in the regulation of various cell processes, including transcription, intracellular trafficking, and chromosome remodeling.
Their deregulation has been associated with the development and progression of various cancer types, the fact which makes them suitable as biomarkers for cancer diagnosis and prognosis.
In recent years, detection of cancer-associated lncRNAs in body fluids of cancer patients has proven itself as an especially valuable method to effectively diagnose cancer.
Cancer diagnosis and prognosis employing circulating lncRNAs are preferential when compared to classical biopsies of tumor tissues, especially due to their noninvasiveness, and have great potential for routine usage in clinical practice.
Thus, this review focuses on summarizing the perspectives of lncRNAs as biomarkers in cancer, based on evaluating their expression profiles determined in body fluids of cancer patients.
American Psychological Association (APA)
Bolha, Luka& Ravnik-Glavač, Metka& Glavač, Damjan. 2017. Long Noncoding RNAs as Biomarkers in Cancer. Disease Markers،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1152482
Modern Language Association (MLA)
Bolha, Luka…[et al.]. Long Noncoding RNAs as Biomarkers in Cancer. Disease Markers No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1152482
American Medical Association (AMA)
Bolha, Luka& Ravnik-Glavač, Metka& Glavač, Damjan. Long Noncoding RNAs as Biomarkers in Cancer. Disease Markers. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1152482
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152482