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Development and Validation of a HPLC-UV Method for the Evaluation of Ellagic Acid in Liquid Extracts of Eugenia uniflora L. (Myrtaceae) Leaves and Its Ultrasound-Assisted Extraction Optimization
Joint Authors
Borges, Leonardo Luiz
Assunção, Paulo Isaac Dias
Conceição, Edemilson Cardoso da
Paula, Joelma Abadia Marciano de
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
A simple HPLC-UV method has been developed and validated for the quantification of ellagic acid (EA) in ethanol extracts of Eugenia uniflora L.
(Myrtaceae) leaves.
The ultrasound-assisted extraction (UAE) optimization was performed using a Box Behnken design (33) combined with response surface methodology to study the effects of the ethanol concentration (%, w/w), extraction time (minutes), and temperature (°C) on the EA concentration.
The optimized results showed that the highest extraction yield of EA by UAE was 26.0 μg mL−1 when using 44% (w/w) ethanol as the solvent, 22 minutes as the extraction time, and 59°C as the extraction temperature.
The concentration of EA in relation to the predicted value was 93.7% ± 0.4.
UAE showed a strong potential for EA extraction.
American Psychological Association (APA)
Assunção, Paulo Isaac Dias& Conceição, Edemilson Cardoso da& Borges, Leonardo Luiz& Paula, Joelma Abadia Marciano de. 2017. Development and Validation of a HPLC-UV Method for the Evaluation of Ellagic Acid in Liquid Extracts of Eugenia uniflora L. (Myrtaceae) Leaves and Its Ultrasound-Assisted Extraction Optimization. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1153010
Modern Language Association (MLA)
Assunção, Paulo Isaac Dias…[et al.]. Development and Validation of a HPLC-UV Method for the Evaluation of Ellagic Acid in Liquid Extracts of Eugenia uniflora L. (Myrtaceae) Leaves and Its Ultrasound-Assisted Extraction Optimization. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1153010
American Medical Association (AMA)
Assunção, Paulo Isaac Dias& Conceição, Edemilson Cardoso da& Borges, Leonardo Luiz& Paula, Joelma Abadia Marciano de. Development and Validation of a HPLC-UV Method for the Evaluation of Ellagic Acid in Liquid Extracts of Eugenia uniflora L. (Myrtaceae) Leaves and Its Ultrasound-Assisted Extraction Optimization. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1153010
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153010