Association of Thrombomodulin Gene C1418T Polymorphism with Susceptibility to Kawasaki Disease in Chinese Children
Joint Authors
Chen, Jia
Tian, Lang
Yang, Zuocheng
Lu, Yapeng
Liu, Rui
Zha, Luting
Yuan, Shan
Huang, Lihua
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-12
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Kawasaki disease (KD) is an acute systemic vasculitis that predominantly affects children and can result in coronary artery lesions (CALs).
Thrombomodulin (TM) is a critical cofactor in the protein C anticoagulant system.
The TM C1418T (rs1042579) polymorphism is associated with a high risk of cardiac-cerebral vascular diseases.
But the association of the TM C1418T polymorphism with susceptibility to KD, CAL formation, and intravenous immunoglobulin (IVIG) resistance is still unclear.
In our study, we examined the TM C1418T polymorphism in 122 children with KD and 126 healthy children and revealed the correlation between the TM C1418T polymorphism and KD, CAL formation, and IVIG resistance.
American Psychological Association (APA)
Lu, Yapeng& Liu, Rui& Zha, Luting& Yuan, Shan& Tian, Lang& Chen, Jia…[et al.]. 2018. Association of Thrombomodulin Gene C1418T Polymorphism with Susceptibility to Kawasaki Disease in Chinese Children. Disease Markers،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1153054
Modern Language Association (MLA)
Lu, Yapeng…[et al.]. Association of Thrombomodulin Gene C1418T Polymorphism with Susceptibility to Kawasaki Disease in Chinese Children. Disease Markers No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1153054
American Medical Association (AMA)
Lu, Yapeng& Liu, Rui& Zha, Luting& Yuan, Shan& Tian, Lang& Chen, Jia…[et al.]. Association of Thrombomodulin Gene C1418T Polymorphism with Susceptibility to Kawasaki Disease in Chinese Children. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1153054
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153054