The Ability of Quantitative, Specific, and Sensitive Point-of-CareChair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases
Joint Authors
Alassiri, Saeed
Parnanen, Pirjo
Rathnayake, Nilminie
Johannsen, Gunnar
Heikkinen, Anna-Maria
Lazzara, Richard
van der Schoor, Peter
van der Schoor, Jan Gerrit
Tervahartiala, Taina
Gieselmann, Dirk
Sorsa, Timo
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-05
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The analysis of the disease-specific oral and systemic biomarkers in saliva and oral fluids (i.e., mouth rinse, gingival crevicular fluid (GCF), and peri-implantitis fluid (PISF)) is demanding.
Several hosts and microbial factors may influence their expression, release, and levels.
The type of saliva/oral fluids utilized for the diagnostics affects the analysis.
High sensitivity and specificities together with sophisticated methods and techniques are essential for valuable outcome.
We describe here recently developed practical, convenient, inexpensive, noninvasive, and quantitative mouth rinse and PISF/GCF/chair-side/point-of-care (PoC) lateral-flow aMMP-8 immunoassays (PerioSafe and ImplantSafe/ORALyser) to detect, predict, and monitor successfully the course, treatment, and prevention of periodontitis and peri-implantitis, respectively.
The tests have been independently and successfully validated to differentiate periodontal and peri-implant health and disease in Finland, Germany, Netherland, Sweden, Turkey, Nigeria, Malawi, and USA.
The clinical use of salivary/oral fluid biomarkers to identify oral and systemic conditions requires additional studies utilizing these noninvasive screening, diagnostic, and preventive aMMP-8 PoC/chair-side technologies.
American Psychological Association (APA)
Alassiri, Saeed& Parnanen, Pirjo& Rathnayake, Nilminie& Johannsen, Gunnar& Heikkinen, Anna-Maria& Lazzara, Richard…[et al.]. 2018. The Ability of Quantitative, Specific, and Sensitive Point-of-CareChair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases. Disease Markers،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1153059
Modern Language Association (MLA)
Alassiri, Saeed…[et al.]. The Ability of Quantitative, Specific, and Sensitive Point-of-CareChair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases. Disease Markers No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1153059
American Medical Association (AMA)
Alassiri, Saeed& Parnanen, Pirjo& Rathnayake, Nilminie& Johannsen, Gunnar& Heikkinen, Anna-Maria& Lazzara, Richard…[et al.]. The Ability of Quantitative, Specific, and Sensitive Point-of-CareChair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1153059
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153059