Investigations of a Possible Chemical Effect of Salvadora persica Chewing Sticks
Joint Authors
Gustafsson, A.
Borg-Karlson, Anna-Karin
Yucel-Lindberg, Tülay
Albabtain, Reham
Azeem, Muhammad
Wondimu, Zenebech
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-18
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Salvadora persica is commonly used chewing sticks in many parts of the world as an oral hygiene tool.
This study measured the amount of benzyl isothiocyanate (BITC) released into the mouth and assessed its retention time in saliva.
The study also tested if the released amount of BITC could potentially be antibacterial or cytotoxic.
Twelve subjects brushed their teeth with fresh Miswak once, twice, and four times.
The amount of BITC in the saliva and in the used brushes was quantified using gas chromatography-mass spectrometry.
The antibacterial effect of BITC and Miswak essential oil (MEO) was tested against Haemophilus influenzae, Aggregatibacter actinomycetemcomitans, and Porphyromonas gingivalis.
The cytotoxic effect on gingival fibroblasts and keratinocytes was tested using MTT.
The highest amount of the active compounds was detected in saliva after using the Miswak tip for once and immediately.
It significantly decreased when the Miswak tip was used more than once and thus after 10 min.
The growth of the tested bacteria was inhibited by MEO and BITC in a dose dependent manner, P.
gingivalis being the most sensitive.
MTT assay showed that BITC and MEO were cytotoxic towards gingival fibroblasts while oral keratinocytes showed resistance.
This study suggests that the Miswak tip should be cut before each use to ensure the maximum effect.
American Psychological Association (APA)
Albabtain, Reham& Azeem, Muhammad& Wondimu, Zenebech& Yucel-Lindberg, Tülay& Borg-Karlson, Anna-Karin& Gustafsson, A.. 2017. Investigations of a Possible Chemical Effect of Salvadora persica Chewing Sticks. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153285
Modern Language Association (MLA)
Albabtain, Reham…[et al.]. Investigations of a Possible Chemical Effect of Salvadora persica Chewing Sticks. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1153285
American Medical Association (AMA)
Albabtain, Reham& Azeem, Muhammad& Wondimu, Zenebech& Yucel-Lindberg, Tülay& Borg-Karlson, Anna-Karin& Gustafsson, A.. Investigations of a Possible Chemical Effect of Salvadora persica Chewing Sticks. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153285
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153285