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Antibiofilm and Anti-Inflammatory Activities of Houttuynia cordata Decoction for Oral Care
Joint Authors
Yumoto, Hiromichi
Sekita, Yasuko
Murakami, Keiji
Amoh, Takashi
Fujiwara, Natsumi
Matsuo, Takashi
Miyake, Yoichiro
Kashiwada, Yoshiki
Hirao, Kouji
Hirota, Katsuhiko
Fujii, Hideki
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-16
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Dental biofilms that form in the oral cavity play a critical role in the pathogenesis of several infectious oral diseases, including dental caries, periodontal disease, and oral candidiasis.
Houttuynia cordata (HC, Saururaceae) is a widely used traditional medicine, for both internal and external application.
A decoction of dried HC leaves (dHC) has long been consumed as a health-promoting herbal tea in Japan.
We have recently reported that a water solution of HC poultice ethanol extract (wHCP) exerts antimicrobial and antibiofilm effects against several important oral pathogens.
It also exhibits anti-inflammatory effects on human keratinocytes.
In our current study, we examined the effects of dHC on infectious oral pathogens and inflammation.
Our results demonstrated that dHC exerts moderate antimicrobial effects against methicillin-resistant Staphylococcus aureus (MRSA) and other oral microorganisms.
dHC also exhibited antibiofilm effects against MRSA, Fusobacterium nucleatum (involved in dental plaque formation), and Candida albicans and inhibitory effects on interleukin-8, CCL20, IP-10, and GROα productions by human oral keratinocytes stimulated by Porphyromonas gingivalis lipopolysaccharide (a cause of periodontal disease), without cytotoxic effects.
This suggests that dHC exhibits multiple activities in microorganisms and host cells.
dHC can be easily prepared and may be effective in preventing infectious oral diseases.
American Psychological Association (APA)
Sekita, Yasuko& Murakami, Keiji& Yumoto, Hiromichi& Hirao, Kouji& Amoh, Takashi& Fujiwara, Natsumi…[et al.]. 2017. Antibiofilm and Anti-Inflammatory Activities of Houttuynia cordata Decoction for Oral Care. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153350
Modern Language Association (MLA)
Sekita, Yasuko…[et al.]. Antibiofilm and Anti-Inflammatory Activities of Houttuynia cordata Decoction for Oral Care. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1153350
American Medical Association (AMA)
Sekita, Yasuko& Murakami, Keiji& Yumoto, Hiromichi& Hirao, Kouji& Amoh, Takashi& Fujiwara, Natsumi…[et al.]. Antibiofilm and Anti-Inflammatory Activities of Houttuynia cordata Decoction for Oral Care. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153350
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153350