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The Role of Parathyroid Hormone and Vitamin D Serum Concentrations in Patients with Cardiovascular Diseases
Joint Authors
Nowalany-Kozielska, Ewa
Ceranowicz, Piotr
Kubiak, Grzegorz M.
Kolaszko, Agnieszka
Morawiec, Beata
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
25-hydroxyvitamin D (25(OH)D) plays a crucial role in human homeostasis.
Its deficiency (vitamin D deficiency—VDD), being common in European population, combined with elevated concentration of parathyroid hormone (PTH), represents a vicious cycle of mechanisms leading to heart failure (HF).
Despite several papers published in that field, the effect of VDD and PTH concentration on cardiovascular system remains unequivocal; thus, the aim of the study was to compare these data among HF and non-HF patients being prospectively enrolled into the study during hospital stay in the cardiology ward.
Patients with HF had higher PTH concentration (85.0 ± 52.6 versus 64.5 ± 31.7, p=0.02) compared to non-HF patients.
Mean PTH values were associated with the clinical status expressed by the New York Heart Association class (NYHA class) (“0”—66.04, “I”—56.57, “II”—72.30, “III”—85.59, and “IV”—144.37 pg/ml, p=0.00004).
Interestingly, neither 25(OH)D (31.5 versus 29.7 ng/ml, p=ns) nor phosphorus (P) (1.23 versus 1.18 mmol/l, p=ns) nor total calcium (Ca2+) concentration (2.33 versus 2.37 mmol/l, p=ns) differed among the groups.
Reassuming PTH serum concentration in contrary to 25(OH)D, P and Ca2+ are significantly raised among the patients with HF and shows significant relationship with the clinical status expressed by the NYHA class.
American Psychological Association (APA)
Kolaszko, Agnieszka& Nowalany-Kozielska, Ewa& Ceranowicz, Piotr& Morawiec, Beata& Kubiak, Grzegorz M.. 2018. The Role of Parathyroid Hormone and Vitamin D Serum Concentrations in Patients with Cardiovascular Diseases. Disease Markers،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1153424
Modern Language Association (MLA)
Kolaszko, Agnieszka…[et al.]. The Role of Parathyroid Hormone and Vitamin D Serum Concentrations in Patients with Cardiovascular Diseases. Disease Markers No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1153424
American Medical Association (AMA)
Kolaszko, Agnieszka& Nowalany-Kozielska, Ewa& Ceranowicz, Piotr& Morawiec, Beata& Kubiak, Grzegorz M.. The Role of Parathyroid Hormone and Vitamin D Serum Concentrations in Patients with Cardiovascular Diseases. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1153424
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153424