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Thyroid-Associated Orbitopathy and Biomarkers: Where We Are and What We Can Hope for the Future
Joint Authors
Turck, Natacha
Eperon, Simone
De Los Angeles Gracia, Maria
Obéric, Aurélie
Hamédani, Mehrad
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Thyroid-associated orbitopathy (TAO) is the most common autoimmune disease of the orbit.
It occurs more often in patients presenting with hyperthyroidism, characteristic of Graves’ disease, but may be associated with hypothyroidism or euthyroidism.
The diagnosis of TAO is based on clinical orbital features, radiological criteria, and the potential association with thyroid disease.
To date, there is no specific marker of the orbital disease, making the early diagnosis difficult, especially if the orbital involvement precedes the thyroid dysfunction.
Summary.
The goal of this review is to present the disease and combine the available data in the literature concerning investigation of TAO biomarkers.
Conclusions.
Despite the progress done in the understanding of TAO disease, some important pieces are still missing.
Typically, for the future, major efforts have to be done in the discovery of new biomarkers, validation of the suspected candidates on multicenter cohorts with standardized methodologies, and establishment of their clinical performances on the specific clinical application fields in order to improve not only the management of the TAO patients but also the therapeutic options and follow-up.
American Psychological Association (APA)
Turck, Natacha& Eperon, Simone& De Los Angeles Gracia, Maria& Obéric, Aurélie& Hamédani, Mehrad. 2018. Thyroid-Associated Orbitopathy and Biomarkers: Where We Are and What We Can Hope for the Future. Disease Markers،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1153578
Modern Language Association (MLA)
Turck, Natacha…[et al.]. Thyroid-Associated Orbitopathy and Biomarkers: Where We Are and What We Can Hope for the Future. Disease Markers No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1153578
American Medical Association (AMA)
Turck, Natacha& Eperon, Simone& De Los Angeles Gracia, Maria& Obéric, Aurélie& Hamédani, Mehrad. Thyroid-Associated Orbitopathy and Biomarkers: Where We Are and What We Can Hope for the Future. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1153578
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153578