Rapid Screening of Chemical Constituents in Rhizoma Anemarrhenae by UPLC-Q-TOFMS Combined with Data Postprocessing Techniques
Joint Authors
Li, Yu-bo
Xu, Yanyan
Yuan, Lei
Shan, Lanlan
Wu, Yuanyuan
Zhang, Yani
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-25
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Rhizoma Anemarrhenae, a famous traditional Chinese medicine (TCM), is the dried rhizome of Anemarrhena asphodeloides Bge.
(Anemarrhena Bunge of Liliaceae).
The medicine presents anti-inflammatory, antipyretic, sedative, and diuretic effects.
The chemical constituents of Rhizoma Anemarrhenae are complex and diverse, mainly including steroidal saponins, flavonoids, phenylpropanoids, benzophenones, and alkaloids.
In this study, UPLC-Q-TOF/MS was used in combination with data postprocessing techniques, including characteristic fragments filter and neutral loss filter, to rapidly classify and identify the five types of substances in Rhizoma Anemarrhenae.
On the basis of numerous literature reviews and according to the corresponding characteristic fragments produced by different types of compounds in combination with neutral loss filtering, we summarized the fragmentation patterns of the main five types of compounds and successfully screened and identified 32 chemical constituents in Rhizoma Anemarrhenae.
The components included 18 steroidal saponins, 6 flavonoids, 4 phenylpropanoids, 2 alkaloids, and 2 benzophenones.
The method established in this study provided necessary data for the study on the pharmacological effects of Rhizoma Anemarrhenae and also provided the basis for the chemical analysis and quality control of TCMs to promote the development of a method for chemical research on TCMs.
American Psychological Association (APA)
Shan, Lanlan& Wu, Yuanyuan& Yuan, Lei& Zhang, Yani& Xu, Yanyan& Li, Yu-bo. 2017. Rapid Screening of Chemical Constituents in Rhizoma Anemarrhenae by UPLC-Q-TOFMS Combined with Data Postprocessing Techniques. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1153634
Modern Language Association (MLA)
Shan, Lanlan…[et al.]. Rapid Screening of Chemical Constituents in Rhizoma Anemarrhenae by UPLC-Q-TOFMS Combined with Data Postprocessing Techniques. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1153634
American Medical Association (AMA)
Shan, Lanlan& Wu, Yuanyuan& Yuan, Lei& Zhang, Yani& Xu, Yanyan& Li, Yu-bo. Rapid Screening of Chemical Constituents in Rhizoma Anemarrhenae by UPLC-Q-TOFMS Combined with Data Postprocessing Techniques. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1153634
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153634