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In Vitro Antioxidant and Antimicrobial Activities of Ephedra gerardiana (Root and Stem) Crude Extract and Fractions
Joint Authors
Khan, Afsar
Khan, Aman
Jan, Gul
Gul Jan, Farzana
Bahadur, Ali
Danish, Muhammad
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The utilization of medicinal plants to treat infectious disease is a common practice in developing countries worldwide.
The present study was aimed at evaluating the crude extracts of Ephedra gerardiana (root and stem) with different chemicals for antioxidant and antimicrobial (fungal and bacterial) potential.
The results revealed that the ethyl acetate fractions of E.
gerardiana (root and stem) have significant free radical scavenging potential with values 2.96±0.39 and 2.73±0.84 while n-butanol and aqueous fractions showed IC502.69±0.26 and 3.44±0.69 µg/ml in stem.
Furthermore, crude extract and fractions also revealed promising antibacterial activities against all tested microbial strains while aqueous fraction showed no activities against Bacillus subtilis, Kleibsiella pneumoniae, and Pseudomonas aeruginosa.
Interestingly, all crude extracts and fractions were nonactive against fungal strain, Aspergillus niger and Aspergillus flavus, as compare to control.
In summary, the Ephedra gerardiana (root and stem) extract and fraction possess antioxidant activities, which might be helpful in preventing or slowing the progress of various oxidative stresses, suggested to be a strong pharmaceutical agent.
American Psychological Association (APA)
Khan, Aman& Jan, Gul& Khan, Afsar& Gul Jan, Farzana& Bahadur, Ali& Danish, Muhammad. 2017. In Vitro Antioxidant and Antimicrobial Activities of Ephedra gerardiana (Root and Stem) Crude Extract and Fractions. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1153647
Modern Language Association (MLA)
Khan, Aman…[et al.]. In Vitro Antioxidant and Antimicrobial Activities of Ephedra gerardiana (Root and Stem) Crude Extract and Fractions. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1153647
American Medical Association (AMA)
Khan, Aman& Jan, Gul& Khan, Afsar& Gul Jan, Farzana& Bahadur, Ali& Danish, Muhammad. In Vitro Antioxidant and Antimicrobial Activities of Ephedra gerardiana (Root and Stem) Crude Extract and Fractions. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1153647
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153647