Adverse Cardiac Remodelling after Acute Myocardial Infarction: Old and New Biomarkers
Joint Authors
Berezin, Alexander E.
Berezin, Alexander A.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-12
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Abstract EN
The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial infarction (AMI) does not decrease regardless of implementation of new technologies supporting opening culprit coronary artery and solving of ischemia-relating stenosis with primary percutaneous coronary intervention (PCI).
Numerous studies have examined the diagnostic and prognostic potencies of circulating cardiac biomarkers in acute coronary syndrome/AMI and heart failure after AMI, and even fewer have depicted the utility of biomarkers in AMI patients undergoing primary PCI.
Although complete revascularization at early period of acute coronary syndrome/AMI is an established factor for improved short-term and long-term prognosis and lowered risk of cardiovascular (CV) complications, late adverse cardiac remodelling may be a major risk factor for one-year mortality and postponded heart failure manifestation after PCI with subsequent blood flow resolving in culprit coronary artery.
The aim of the review was to focus an attention on circulating biomarker as a promising tool to stratify AMI patients at high risk of poor cardiac recovery and developing HF after successful PCI.
The main consideration affects biomarkers of inflammation, biomechanical myocardial stress, cardiac injury and necrosis, fibrosis, endothelial dysfunction, and vascular reparation.
Clinical utilities and predictive modalities of natriuretic peptides, cardiac troponins, galectin 3, soluble suppressor tumorogenicity-2, high-sensitive C-reactive protein, growth differential factor-15, midregional proadrenomedullin, noncoding RNAs, and other biomarkers for adverse cardiac remodelling are discussed in the review.
American Psychological Association (APA)
Berezin, Alexander E.& Berezin, Alexander A.. 2020. Adverse Cardiac Remodelling after Acute Myocardial Infarction: Old and New Biomarkers. Disease Markers،Vol. 2020, no. 2020, pp.1-21.
https://search.emarefa.net/detail/BIM-1153749
Modern Language Association (MLA)
Berezin, Alexander E.& Berezin, Alexander A.. Adverse Cardiac Remodelling after Acute Myocardial Infarction: Old and New Biomarkers. Disease Markers No. 2020 (2020), pp.1-21.
https://search.emarefa.net/detail/BIM-1153749
American Medical Association (AMA)
Berezin, Alexander E.& Berezin, Alexander A.. Adverse Cardiac Remodelling after Acute Myocardial Infarction: Old and New Biomarkers. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-21.
https://search.emarefa.net/detail/BIM-1153749
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153749