The Association between Glomerular Filtration Rate Estimated Using Different Equations and Mortality in the Japanese Community-Based Population: The Yamagata (Takahata) Study
Joint Authors
Kabasawa, Asami
Suzuki, Natsuko
Kamei, Keita
Watanabe, Sayumi
Araumi, Akira
Matsuki, Eri
Kon, Soichiro
Oyama, Midori
Ishizawa, Kenichi
Yamashita, Hidetoshi
Ueno, Yoshiyuki
Ichikawa, Kazunobu
Kubota, Isao
Konta, Tsuneo
Kayama, Takamasa
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
To evaluate renal function, the indices of estimated glomerular filtration rate (eGFR) obtained using several equations, including the Japanese versions of the serum creatinine-based MDRD equation (eGFRcreat), Chronic Kidney Disease Epidemiology Collaboration equation (eGFR-EPI), and serum cystatin C-based equation (eGFRcys), are utilized.
This study prospectively examined the association between these eGFR values and all-cause mortality during a 12-year observational period in a community-based population.
Methods and Results.
The subjects of this study were 1312 participants undergoing a health checkup, aged ≥40 years.
In the total population, the mean eGFR values (mL·min−1·1.73 m−2) were 81.5 for eGFRcreat, 78.1 for eGFR-EPI, and 76.6 for eGFRcys.
There were 141 deaths during the observation period, and the area under the receiver operating characteristic curve for predicting mortality was 0.59 for eGFRcreat, 0.67 for eGFR-EPI, and 0.70 for eGFRcys (all P<0.01).
In the Cox proportional analysis adjusted for age and sex, eGFRcys, but not eGFRcreat and eGFR-EPI, showed a significant association with all-cause mortality (per 15 mL·min−1·1.73 m−2 decrease: hazard ratio 1.40, 95% confidence interval 1.18–1.67).
Conclusions.
This study revealed that eGFRcys showed lower values than eGFRcreat and eGFR-EPI and was significantly associated with all-cause mortality in the Japanese community-based population.
American Psychological Association (APA)
Kabasawa, Asami& Konta, Tsuneo& Suzuki, Natsuko& Kamei, Keita& Watanabe, Sayumi& Araumi, Akira…[et al.]. 2018. The Association between Glomerular Filtration Rate Estimated Using Different Equations and Mortality in the Japanese Community-Based Population: The Yamagata (Takahata) Study. Disease Markers،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1153763
Modern Language Association (MLA)
Kabasawa, Asami…[et al.]. The Association between Glomerular Filtration Rate Estimated Using Different Equations and Mortality in the Japanese Community-Based Population: The Yamagata (Takahata) Study. Disease Markers No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1153763
American Medical Association (AMA)
Kabasawa, Asami& Konta, Tsuneo& Suzuki, Natsuko& Kamei, Keita& Watanabe, Sayumi& Araumi, Akira…[et al.]. The Association between Glomerular Filtration Rate Estimated Using Different Equations and Mortality in the Japanese Community-Based Population: The Yamagata (Takahata) Study. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1153763
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153763