Neuroendocrine Factors and Head and Neck Squamous Cell Carcinoma: An Affair to Remember
Joint Authors
Tanase, Cristiana Pistol
Căruntu, Constantin
Boda, Daniel
Căruntu, Ana
Voiculescu, Vlad
Ghita, Mihaela
Lupu, Mihai
Ion, Alexandra
Solomon, Iulia
Constantin, Carolina
Neagu, Monica
Albulescu, Radu
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-08
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Head and neck squamous cell carcinoma (HNSCC) is one of the most aggressive malignancies.
Therefore, the major goal of cancer treatment is inhibition of tumor cell growth and of metastasis development.
In order to choose the best management option for HNSCC patients, we need to identify reliable prognostic factors and to develop new molecular techniques in order to obtain a better understanding of therapy resistance.
By acting as neurohormones, neurotransmitters, or neuromodulators, the neuroendocrine factors are able to signal the maintenance of physiological homeostasis or progression to malignant disease.
Certain neuropeptides possess strong antitumor properties acting as tumor suppressors and immunomodulators, providing additional benefits for future potential therapeutic strategies.
In light of the current understanding, cancer starts as a localized disease that can be effectively treated if discovered on proper time.
Unfortunately, more than often cancer cells migrate to the surrounding tissues generating distant metastases, thus making the prognosis and survival in this stage much worse.
As cellular migration is mandatory for tumor invasion and metastasis development, searching for alternate controllers of these processes, such as the neuroendocrine factors, it is an active tremendous task.
American Psychological Association (APA)
Solomon, Iulia& Voiculescu, Vlad& Căruntu, Constantin& Lupu, Mihai& Ion, Alexandra& Ghita, Mihaela…[et al.]. 2018. Neuroendocrine Factors and Head and Neck Squamous Cell Carcinoma: An Affair to Remember. Disease Markers،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1153797
Modern Language Association (MLA)
Solomon, Iulia…[et al.]. Neuroendocrine Factors and Head and Neck Squamous Cell Carcinoma: An Affair to Remember. Disease Markers No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1153797
American Medical Association (AMA)
Solomon, Iulia& Voiculescu, Vlad& Căruntu, Constantin& Lupu, Mihai& Ion, Alexandra& Ghita, Mihaela…[et al.]. Neuroendocrine Factors and Head and Neck Squamous Cell Carcinoma: An Affair to Remember. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1153797
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153797